IP Library › Granted Patent US 8,334,295
Granted Patent B2
US 8,334,295 · App. 12/215,450 · Granted Dec 18, 2012

Pyrimidine derivatives as HIV reverse transcriptase inhibitors

Assignee: Korea Research Institute of Chemical Technology
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Quick Facts
Patent No.
US 8,334,295
App. No.
12/215,450
Granted
Dec 18, 2012
Kind
B2
Abstract

The invention is related to compounds of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

Claims (2)

1. The compound 3-(3-ethyl-5-isopropyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carbonyl)-5-methylbenzonitrile, or a pharmaceutically acceptable salt and/or ester thereof.

2. A pharmaceutical composition comprising a therapeutically effective amount of 3-(3-Ethyl-5-isopropyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carbonyl)-5-methyl-benzonitrile, or a pharmaceutically acceptable salt and/or ester thereof, and a pharmaceutically acceptable carrier.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY DATA OF THE ASSIGNMENT PREVIOUSLY RECORDED ON REEL 023618 FRAME 0087. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT OF ASSIGNOR'S INTEREST. Recorded Jul 3, 2012
From: GILEAD SCIENCES, INC.
To: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Reel/Frame 028497/0743 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2009
From: GILEAD SCIENCES, INC.
To: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Reel/Frame 023618/0087 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE PREVIOUSLY RECORDED ON REEL 021736 FRAME 0498. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 7, 2009
From: GUO, HONGYAN; KIM, CHOUNG U.; LEE, ILL Y.; MITCHELL, MICHAEL L.; RHODES, GERRY; SON, JONG C.; XU, LIANHONG
To: GILEAD SCIENCES, INC.; KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Reel/Frame 023612/0303 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2008
From: GUO, HONGYAN; KIM, CHOUNG U.; LEE, ILL Y.; MITCHELL, MICHAEL L.; RHODES, GERRY; SON, JONG C.; XU, LIANHONG
To: GILEAD SCIENCES, INC.
Reel/Frame 021736/0498 →
Continuity (3)
Provisional Application 60959676 · Jul 16, 2007
Provisional Application 60937756 · Jun 29, 2007
Related Publication 20110076276A1 · Mar 31, 2011