Method and device for measuring reflected optical radiation
View Patent ↗The present invention provides an optics assembly, a reflectometer, and a diagnostic device for providing quantitative measurement of optical radiation reflected from a sampling area on an assay matrix. The reflectometer includes an optical radiation source and a detector. The optical radiation source and the detector are mounted in a single plane. An optics assembly is configured to direct the illumination from the optical radiation source to the sampling area on the assay matrix and to direct the radiation diffusely reflected from the sampling area to the detector. The optics assembly is positioned over the face of the circuit board having the optical radiation source and detector mounted directly thereto. The present invention also provides a method for determining the presence of one or more selected analytes in a sample employing a plurality of sampling areas on one or more assay matrixes.
1. An assay strip meter comprising:
at least one optical radiation emitter;
a plurality of assay strips containing chemical reagents for detecting the presence of one or more analytes in a sample, wherein each assay strip contains a plurality of sample areas that contain a plurality of reagents that chemically react with the sample; and
a plurality of detectors, wherein the plurality of detectors each correspond to a sampling area, at least one of said plurality of detectors corresponding to a first of said plurality of assay strips and at least a second of said plurality of detectors simultaneously corresponding to a second of said plurality of assay strips;
a further detector, wherein the further detector corresponds to a reference area independent of the plurality of assay strips.
2. The assay strip meter of claim 1 , wherein a plurality of sample-reagent mixtures are measured one of simultaneously and sequentially.
3. The assay strip meter of claim 1 , wherein optical radiation emitted from the optical radiation emitter is split and directed to the plurality of sample areas and the reference area.
4. The assay strip meter of claim 3 , further comprising a plurality of totally internal-reflecting elements adapted to direct the optical radiation emitted from the optical radiation emitter.
5. The assay strip meter of claim 3 , wherein the optical radiation emitter is a light emitting diode.
6. The assay strip meter of claim 5 , wherein the optical radiation emitted from the light emitting diode is split four ways.
7. The assay strip meter of claim 1 , wherein said plurality of assay strips is two assay strips and the plurality of sample-reagent mixtures of said two assay strips are measured simultaneously.
8. The assay strip meter of claim 1 , wherein the further detector provides a control for the sampling areas.