IP Library Granted Patent US 8,336,553
Granted Patent B2
US 8,336,553 · App. 12/235,538 · Granted Dec 25, 2012

Auto-titration of positive airway pressure machine with feedback from implantable sensor

Assignee: Medtronic Xomed, Inc.
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Quick Facts
Patent No.
US 8,336,553
App. No.
12/235,538
Granted
Dec 25, 2012
Kind
B2
Abstract

Systems and methods for detecting and treating an obstructive sleep apnea event are disclosed herein. The systems and methods may use an electrical output generating ionic polymer metal composite sensor attached to a region in an airway passage in an oral cavity. The electrical output may be wirelessly transmitted as a signal for indication of an obstructive sleep apnea event. The signal may be further analyzed by a positive airway pressure system for treatment of the obstructive sleep apnea event.

Claims (30)

1. A system to treat obstructive sleep apnea, comprising:

an ionic polymer metal composite (IPMC) sensor adapted to be attached to a region in an airway passage in an oral cavity which generates an electrical output when a change in shape of the airway passage in the oral cavity occurs; and

a transmitter device electrically coupled to the IPMC sensor and configured to wirelessly transmit at least one electronic signal;

a sensor analyzer wirelessly electronically coupled to the transmitter device for wirelessly receiving and for analyzing the at least one electronic signal and generating an output based thereon; and

a positive airway pressure machine electronically coupled to the sensor analyzer for generating an optimum input pressure to treat the sleep apnea event according to the output from the sensor analyzer.

2. The system of claim 1 wherein the output of the sensor analyzer is generated in a linear or non-linear or adaptive fashion.

3. The system of claim 2 wherein the output generation is based on neural network algorithms.

4. The system of claim 3 wherein the IPMC sensor includes an electro active polymer material.

5. The system of claim 4 wherein the IPMC sensor is configured as an elongated strip.

6. The system of claim 5 wherein the IPMC sensor is adapted to be implanted into the soft palate.

7. The system of claim 1 wherein the IPMC sensor does not include an external power source.

8. The system of claim 1 wherein the positive airway pressure machine automatically titrates an amount of pressure delivered to a patient.

9. The system of claim 1 wherein the positive airway pressure machine includes a pressure controller.

10. The system of claim 9 wherein the pressure controller is coupled to a pressure sensor which outputs a pressure signal.

11. The system of claim 10 wherein the pressure signal is also used to generate the optimum input pressure.

12. A method to treat obstructive sleep apnea in a patient, the method comprising:

attaching an ionic polymer metal composite (IPMC) sensor to a region in an airway passage in an oral cavity of the patient;

generating at least one electronic signal from the IPMC sensor when a change in shape of the mouth or larynx occurs from an obstructive sleep apnea event and independent of pressure in the airway passage;

wirelessly transmitting the at least one electronic signal;

receiving and analyzing the at least one electronic signal at a location external the patient;

generating an output based on the at least one electronic signal; and

generating an optimum input pressure at least partially based on the output, for a positive airway pressure machine to treat the obstructive sleep apnea event.

13. The method of claim 12 additionally comprising generating at least one additional electronic signal from a second ionic polymer metal composite (IPMC) sensor.

14. The system of claim 12 wherein the output is generated in a linear or non-linear or adaptive fashion.

15. The system of claim 12 wherein the output generation is based on neural network algorithms.

16. The method of claim 12 additionally comprising generating a pressure signal from a pressure sensor.

17. The method of claim 16 wherein the pressure signal is also used to generate the optimum input sensor.

18. The method of claim 12 wherein the output is the sole input to generate the optimum input pressure.

19. The method of claim 12 wherein wirelessly transmitting the at least one electronic signal is performed by a transmitter device which is coupled to the IPMC sensor.

20. The method of claim 12 , wherein the step of attaching the IPMC sensor includes implanting the IPMC sensor into a soft palate of the patient.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 29, 2011
From: PAVAD MEDICAL, INC.
To: MEDTRONIC XOMED, INC.
Reel/Frame 027288/0878 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 15, 2008
From: BHAT, NIKHIL D.; HEGDE, ANANT V.; YUNG, CHARISSE M.; CHOI, GEORGE Y.
To: PAVAD MEDICAL, INC.
Reel/Frame 021981/0810 →
Continuity (6)
Continuation In Part 11613027 · Dec 19, 2006
Continuation In Part 11355927 · Feb 15, 2006
Continuation In Part 11233493 · Sep 21, 2005
Continuation In Part 10946435 · Sep 21, 2004
Provisional Application 61055405 · May 22, 2008
Related Publication 20090078257A1 · Mar 26, 2009