Prepolymerizable surface active monomers with both fluorine-containing groups and hydrophilic groups
View Patent ↗Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to surface modifying polymers.
1. A reactive surface active monomer having the structure below:
2. A polymerizable monomer mixture comprising at least one monomer of claim 1 .
3. The polymerizable monomer mixture of claim 2 wherein a relative weight % of the polymerizable surface active monomer as compared to the total monomer mix weight % is from about 0.01% to about 10%.
4. The polymerizable monomer mixture of claim 2 wherein a relative weight % of the polymerizable surface active monomer as compared to the total monomer mix weight % is about 0.1% to about 5%.
5. The polymerizable monomer mixture of claim 2 wherein a relative weight % of the polymerizable surface active monomer as compared to the total monomer mix weight % is about 0.2% to about 1%.
6. The monomer mixture of claim 2 further comprising at least one hydrophilic monomer.
7. The monomer mixture of claim 6 wherein the hydrophilic monomer is selected from the group consisting of ethylenically unsaturated lactam-containing monomers, methacrylic acids, acrylic acids, (meth)acrylic substituted alcohols, (meth)acrylamides, vinyl carbonate, vinyl carbamate monomers, oxazolinone monomers, glycerol methacrylate, polyethyleneglycol monomethacrylate and mixtures thereof.
8. The monomer mixture of claim 2 further comprising at least one silicone monomer.
9. The monomer mixture of claim 8 wherein the at least one silicone monomer is a bulky polysiloxanylalkyl (meth)acrylic monomer.
10. The monomer mixture of claim 8 wherein the at least one silicone monomer is selected from the group consisting of methacryloxypropyl tris(trimethylsiloxy)silane (TRIS), pentamethyldisiloxanylmethylmethacrylate, tris(trimethylsiloxy)methacryloxy propylsilane, phenyltetramethyldisiloxanylethyl acrylate, methylbis(trimethylsiloxy)methacryloxymethyl silane and mixtures thereof.
11. The monomer mixture of claim 2 further comprising a crosslinking agent.
12. A surface modified medical device comprising a medical device manufactured from a monomer having the structure below:
13. The medical device of claim 12 wherein the medical device has at least one of the property selected from the group consisting of oxygen permeability, hydrolytically stability, biologically inertness, and transparency.
14. The medical device of claim 12 wherein the medical device has a three-dimensional networks which permits the transport of oxygen.
15. The medical device of claim 12 wherein the medical device is an optically clear, strong and hydrophilic medical device.
16. The medical device of claim 15 wherein the medical device is an ophthalmic lens.
17. The medical device of claim 16 wherein the medical device is a contact lens.
18. The medical device of claim 16 wherein the medical device is an intraocular lens.