Biomedical devices
View Patent ↗Biomedical devices are provided herein which are formed from a polymerization product of a monomeric mixture comprising (a) one or more esterified aminoalcohol monomers; and (b) one or more biomedical device-forming monomers.
1. A hydrogel contact lens formed from a polymerization product of a monomeric mixture comprising (a) one or more esterified aminoalcohol monomers of the general Formula I:
wherein X is a polymerizable ethylenically unsaturated organic ester-containing radical, R 1 is hydrogen, or a C 1 -C 30 non-polymerizable hydrocarbyl group optionally substituted with a hydroxyl group, and R 2 is a hydroxyl-containing non-polymerizable group; and (b) one or more lens forming comonomers.
2. The contact lens of claim 1 , wherein X is a vinyl ester-containing radical.
3. The contact lens of claim 1 , wherein X is a (meth)acrylate ester-containing radical.
4. The contact lens of claim 1 , wherein R 2 is a hydroxyl substituted C 1 -C 6 alkyl group.
5. The contact lens of claim 1 , wherein R 1 is an alcohol of the general formula —R 3 OH wherein R 3 is a straight or branched C 1 -C 30 alkyl group and R 2 is a hydroxyl substituted C 1 -C 6 alkyl group.
6. The contact lens of claim 1 , wherein the esterified aminoalcohol monomer is represented by the structure of general Formula II:
wherein X and R 1 have the aforestated meanings and R 2 is a straight or branched C 1 -C 6 alkyl group, and the lens-forming comonomer is a silicone-containing monomer.
7. The contact lens of claim 6 , wherein R 1 is an alcohol of the general formula —R 7 OH wherein R 7 is a straight or branched C 1 -C 6 alkyl group and R 2 is a C 1 -C 6 alkyl group.
8. The contact lens of claim 1 , wherein the lens-forming comonomer is a silicone-containing monomer.
9. The contact lens of claim 1 , wherein the monomeric mixture further comprises a hydrophilic monomer.
10. The contact lens of claim 9 , wherein the hydrophilic monomer includes an acrylic-containing monomer.
11. The contact lens of claim 9 , wherein the hydrophilic monomer includes a vinyl-containing monomer.
12. The contact lens of claim 9 , wherein the hydrophilic monomer includes at least one member selected from the group consisting of N,N-dimethylacrylamide and N-vinylpyrrolidone.