IP Library Granted Patent US 8,666,483
Granted Patent B2
US 8,666,483 · App. 12/250,141 · Granted Mar 4, 2014

System for cardiac medical condition detection and characterization

Inventor: Hongxuan Zhang (Schaumburg, IL)
Assignee: Siemens Medical Solutions USA, Inc.
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Quick Facts
Patent No.
US 8,666,483
App. No.
12/250,141
Granted
Mar 4, 2014
Kind
B2
Abstract

A system and method provides monitoring for atrial fibrillation. A data acquisition processor acquires a cardiac signal data stream from a patient and a wave detector detects an R-wave in a cardiac signal of the data stream. A T-wave in the cardiac signal occurring after the detected R-wave and a Q-wave in a subsequent cardiac signal of the data stream is also detected by the wave detector. A filter provides signal gating and extraction of data representing a Region of Interest (ROI) time window from the detected T-wave to the Q-wave. An integration processor detects characteristics of a P wave signal occurring within the ROI time window. At least one of the detected P wave characteristics is compared to characteristics derived from data representing at least one P wave signal and generating an output signal in response to the comparison for use in determining if the patient is in atrial fibrillation.

Claims (96)

1. A system for monitoring atrial fibrillation comprising:

a data acquisition processor for acquiring a cardiac signal data stream from a patient;

a wave detector for detecting an R-wave in a cardiac signal of the data stream, said wave detector detecting a T-wave in the cardiac signal occurring after the detected R-wave and a Q point in a successive subsequent cardiac signal of the data stream;

a filter for signal gating and extraction of data representing a Region of Interest (ROI) time window from substantially the end of the detected T-wave to the detected successive subsequent Q point;

an integration processor for detecting characteristics of a P wave signal occurring within the ROI time window, comparing a latency of the P wave comprising a time duration within the ROI time window that the P wave occurs relative to both the T-wave and the Q-wave within the ROT time window, to corresponding characteristics derived from data representing at least one P wave signal and generating an output signal in response to the comparison for use in determining if the patient is in atrial fibrillation.

2. The system as claimed in claim 1 , wherein the detected characteristics include an amplitude of the P wave and an entropy of the cardiac signal.

3. The system of claim 2 , wherein the entropy of the cardiac signal is determined according to:

H

(

P

)

=

-

s

S

P

(

s

)

·

log

P

(

s

)

wherein s is the ROI window.

4. The system of claim 2 , further comprising a processor for performing Max-min analysis; multi-beat averaging; and heart rate variability (HRV) and RR interval analysis.

5. The system of claim 4 , wherein said integration processor generates the output signal in response to any combination of detecting the entropy of the cardiac signal within the T-Q window; Max-min analysis; multi-beat averaging; and heart rate variability (HRV) and RR interval analysis.

6. The system of claim 1 , further including a repository for storing a plurality of data sets from which the data representing at least one P wave signal is selected.

7. The system of claim 6 , wherein the data of each of the plurality of data sets represent at least one P wave signal associated with a respective physiological characteristic.

8. The system of claim 7 , wherein the associated physiological characteristics include at least one of age, weight, gender, sex and ethnicity.

9. The system of claim 1 , further comprising a transmitter for automatically transmitting the output signal to a remote unit for viewing and analysis by a user.

10. The system of claim 1 , further comprising a buffer for recording the output signal generated by the integration processor.

11. The system of claim 1 , further comprising an alarm for notifying a user in response to a determination the patient is in atrial fibrillation.

12. The system of claim 11 , wherein said alarm receives the output signal from said integration processor and generates at least one of an audible and visual alarm in response to a determination the patient is in atrial fibrillation.

13. A method for detecting atrial fibrillation, said method comprising the activities of:

acquiring a cardiac signal data stream;

detecting an R-wave in a cardiac signal of the cardiac signal data stream;

detecting a T-wave in the cardiac signal and a Q point in a successive subsequent cardiac signal of the data stream;

filtering the cardiac signal to obtain a T-Q window from substantially the end of the detected T-wave to the detected successive subsequent Q point;

detecting characteristics of a P wave within the T-Q window; and

comparing the detected P wave characteristics including a latency of the P wave comprising a time duration within the T-Q time window that the P wave occurs relative to both the T-wave and the Q-wave within the T-Q time window, to a threshold value; and

determining if a patient is in atrial fibrillation in response to the comparison.

14. The method as claimed in claim 13 , wherein the activity of detecting characteristics includes determining an amplitude of the P wave and an entropy of the cardiac signal within the T-Q window.

15. The method as claimed in claim 13 , wherein said activity of determining entropy is performed according to:

H

(

P

)

=

-

s

S

P

(

s

)

·

log

P

(

s

)

wherein s is the ROI window.

16. The method as claimed in claim 13 , further comprising the activity of transmitting the output signal to a remote unit for viewing and analysis by a user.

17. The method as claimed in claim 13 , further comprising the activity of recording the output signal generated by the integration processor.

18. The method as claimed in claim 13 , further comprising the activity of determining the patient is in atrial fibrillation in response to the comparison and notifying a user.

19. The method as claimed in claim 13 , further comprising the activities of:

performing at least one of Max-min analysis, multi-beat averaging and heart rate variability (HRV) and RR interval analysis; and

determining if atrial fibrillation has occurred in response to both said activities of comparing and performing.

20. A method for detecting atrial fibrillation, said method comprising the activities of:

acquiring a cardiac signal data stream;

detecting an R-wave in a cardiac signal of the cardiac signal data stream;

detecting a T-wave in the cardiac signal and a Q point in a successive subsequent cardiac signal of the data stream;

filtering the cardiac signal to obtain a T-Q window from substantially the end of the detected T-wave to the detected successive subsequent Q point;

detecting characteristics of a P wave within the T-Q window; and

comparing the detected P wave characteristics including a latency of the P wave comprising a time duration within the T-Q time window that the P wave occurs relative to both the T-wave and the Q-wave within the T-Q time window, to a threshold value; and

determining if a patient is in atrial fibrillation in response to the comparison.

21. The method as claimed in claim 20 , further comprising the activities of:

comparing the detected P wave characteristics including an amplitude of the P wave, to said threshold value.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 11, 2022
From: ICE CAP
To: PIXART IMAGING INC.
Reel/Frame 061639/0342 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 30, 2021
From: ALLIED SECURITY TRUST I
To: ICE CAP, SERIES 106 OF ALLIED SECURITY TRUST I
Reel/Frame 058601/0037 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 23, 2021
From: SIEMENS HEALTHCARE GMBH
To: ALLIED SECURITY TRUST I
Reel/Frame 058960/0371 →
CORRECTIVE ASSIGNMENT TO CORRECT THE EXECUTION DATE OF ASSIGNMENT 3, ASSIGNOR SIEMENS MEDICAL SOLUTIONS USA, INC. TO SIEMENS HEALTHCARE GMBH PREVIOUSLY RECORDED ON REEL 043379 FRAME 0673. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT OF INVENTOR RIGHTS.. Recorded Dec 2, 2020
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 056112/0540 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2017
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 043379/0673 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 4, 2008
From: ZHANG, HONGXUAN
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 021782/0034 →
Continuity (2)
Provisional Application 60982249 · Oct 24, 2007
Related Publication 20090112110A1 · Apr 30, 2009