IP Library Granted Patent US 8,958,862
Granted Patent B2
US 8,958,862 · App. 12/253,813 · Granted Feb 17, 2015

Implantable device including a resorbable carrier

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Quick Facts
Patent No.
US 8,958,862
App. No.
12/253,813
Granted
Feb 17, 2015
Kind
B2
Abstract

An implantable device for body tissue, including an electrical subsystem that flexes within and interfaces with body tissue and a carrier that operates in the following two modes: provides structural support for the electrical subsystem during implantation of the device in body tissue and allows flexing of the electrical subsystem after implantation of the device in body tissue. The implantable device is preferably designed to be implanted into the brain, spinal cord, peripheral nerve, muscle, or any other suitable anatomical location. The implantable device, however, may be alternatively used in any suitable environment and for any suitable reason.

Claims (73)

1. An implantable electrode device, comprising:

a) a carrier extending along a first carrier length from a proximal carrier portion to a distal carrier portion having a distal carrier end;

b) a first electrical subsystem, comprising:

i) at least one electrode site;

ii) an electrode substrate supporting the at least one electrode site, wherein at least a portion of the electrode substrate supporting the at least one electrode site is woven with the carrier so that the at least one electrode site has an exposed surface facing outwardly from the electrode substrate opposite the carrier; and

iii) an electrical connector extending from the at least one electrode site to a proximal connector portion adjacent to the proximal carrier portion; and

c) wherein the carrier is of a bioresorbable material that is absorbable into body tissue after implantation of the electrode device comprising the carrier and the first electrical subsystem, thereby leaving the at least one electrode site facing outwardly toward the body tissue from the supporting electrode substrate.

2. The implantable electrode device of claim 1 , wherein the first electrical subsystem is flexible after absorption of the carrier into body tissue.

3. The implantable electrode device of claim 1 wherein the bioresorbable material of the carrier is selected from the group consisting of polyglycolide, polylactide, a magnesium alloy, and a corrodible iron alloy.

4. The implantable electrode device of claim 1 , wherein the carrier has a tubular shape.

5. The implantable electrode device of claim 4 wherein there are a plurality of electrode sites supported by the electrode substrate and wherein the electrode substrate is woven with the tubular carrier so that the plurality of electrode sites extend both circumferentially and axially relative to the first carrier length.

6. The implantable electrode device of claim 4 wherein the tubular carrier has a diameter of about one millimeter.

7. The implantable electrode device of claim 1 wherein the carrier has a woven structure.

8. The implantable electrode device of claim 1 , wherein the at least one electrode site of the first electrical subsystem is configured to interface with neural tissue.

9. The implantable electrode device of claim 8 , wherein the first electrical subsystem includes a plurality of electrode sites that are configured to electrically stimulate different portions of neural tissue.

10. The implantable electrode device of claim 1 wherein there are a plurality of electrode sites supported by the electrode substrate and wherein the electrode substrate is woven with the carrier so that the plurality of electrode sites extend both circumferentially and axially relative to the first carrier length.

11. The implantable electrode device of claim 1 wherein there are a plurality of electrode sites supported by the electrode substrate, and wherein the plurality of electrode sites are configured to electrically record different portions of neural tissue.

12. The implantable electrode device of claim 1 wherein the electrode substrate is of a thin-film polymer.

13. The implantable electrode device of claim 12 , wherein the thin-film polymer is selected from the group consisting of parylene and silicone.

14. The implantable electrode device of claim 1 , wherein the electrode substrate has a tubular shape.

15. The implantable electrode device of claim 1 wherein the electrode substrate has a series of perforations that axially extend in a discontinuous manner along a second electrode substrate length.

16. The implantable electrode device of claim 1 wherein the electrode substrate is a thin-film substrate.

17. The implantable electrode device of claim 1 wherein the first electrical subsystem has an elongated, substantially planar shape.

18. The implantable electrode device of claim 1 wherein the proximal connector portion of the first electrical subsystem is electrically connectable to a second electrical subsystem that is configured to control the at least one electrode site.

19. The implantable electrode device of claim 1 wherein the electrical connector is a flexible ribbon cable.

20. The implantable electrode device of claim 1 wherein a lumen extends through the carrier along the first carrier length from the proximal carrier portion to the distal carrier end.

21. The implantable electrode device of claim 20 wherein the lumen is configured to receive a stylet having a sharpened end adapted to extend outwardly from the distal carrier end.

22. The implantable electrode device of claim 1 wherein the electrode substrate includes longitudinal and circumferential bridge strips, and wherein one or more longitudinal bridge strip is connected by the circumferential bridge strips, thereby defining a series of discontinuous perforations in the electrode substrate of the first electrical subsystem.

23. The implantable electrode device of claim 1 wherein the carrier comprises an inner tubular sidewall disposed inside an outer tubular sidewall with the first electrical subsystem located between the inner and outer carrier sidewalls, but with the exposed surface of the at least one electrode site facing outwardly from the electrode substrate opposite the inner and outer carrier sidewalls.

24. The implantable electrode device of claim 1 wherein the bioresorhable material of the carrier is completely absorbable into body tissue within about one month after implantation of the electrode device.

25. The implantable electrode device of claim 1 wherein the bioresorhable material of the carrier is completely absorbable into body tissue within about one year after implantation of the electrode device.

26. The implantable electrode device of claim 1 wherein the first electrical subsystem defines a perforation, and wherein the carrier is anchorable in body tissue in the perforation.

27. An implantable electrode device, comprising:

a) a carrier extending along a first carrier length from a proximal carrier portion to a distal carrier portion;

b) an electrical subsystem, comprising:

i) a plurality of electrode sites;

ii) an electrode substrate supporting the plurality of electrode sites, wherein at least a portion of the electrode substrate supporting the plurality of electrode sites is woven with the carrier so that the electrode sites are both circumferentially and axially disposed relative to the first carrier length and wherein the plurality of electrode sites have respective exposed surfaces facing outwardly from the electrode substrate opposite the carrier; and

iii) an electrical connector extending from each of the plurality of electrode sites to a proximal connector portion adjacent to the proximal carrier portion; and

c) wherein the carrier is of a bioresorbable polymer selected from the group consisting of polyglycolide, polylactide, a magnesium alloy, and a corrodible iron alloy and that is absorbable into body tissue after implantation of the electrode device comprising the carrier and the electrical subsystem, thereby leaving the plurality of electrode sites facing outwardly toward the body tissue from the supporting electrode substrate.

28. The implantable electrode device of claim 27 wherein the carrier has a tubular shape.

29. The implantable electrode device of claim 27 wherein a lumen extends through the carrier along the first carrier length from the proximal carrier portion to a distal carrier end of the distal carrier portion.

30. The implantable electrode device of claim 27 wherein the electrode substrate has a tubular shape.

31. The implantable electrode device of claim 27 wherein the electrode substrate is substantially planar.

32. An implantable electrode device, comprising:

a) a carrier, comprising:

i) a woven carrier sidewall extending along a first carrier length from a proximal carrier portion to a distal carrier portion having a distal carrier end; and

ii) a lumen extending through the carrier along the first carrier length from the proximal carrier portion to the distal carrier end;

b) an electrical subsystem, comprising:

i) at least one electrode site;

ii) an electrode substrate supporting the electrode site, wherein at least a portion of the electrode substrate supporting the at least one electrode site is interwoven with the carrier sidewall so that the at least one electrode site has an exposed electrode surface facing outwardly, away from the electrode substrate interwoven with the carrier; and

iii) an electrical connector extending from the at least one electrode site to a proximal connector portion adjacent to the proximal carrier portion; and

c) wherein the carrier sidewall is of a bioresorbable polymer that is absorbable into body tissue after implantation of the electrode device comprising the carrier interwoven with the electrode substrate, thereby leaving the at least one electrode site facing outwardly, away from the supporting electrode substrate.

33. The implantable electrode device of claim 32 wherein the carrier sidewall has a tubular shape.

34. The implantable electrode device of claim 32 wherein the electrode substrate has a tubular shape.

35. The implantable electrode device of claim 32 wherein the electrical subsystem has an elongated, substantially planar shape.

36. An implantable electrode device, comprising:

a) a carrier comprising a carrier sidewall extending along a carrier length from a proximal carrier portion to a distal carrier portion having a distal carrier end;

b) an electrical subsystem, comprising:

i) a plurality of electrode sites;

ii) an electrode substrate supporting the plurality of electrode sites, wherein the electrode substrate is supported by the carrier with the plurality of electrode sites extending both circumferentially and axially relative to the carrier length and wherein the electrode sites each have an exposed surface facing outwardly from the electrode substrate opposite the carrier; and

iii) an electrical connector extending from each of the plurality of electrode sites to a proximal connector portion adjacent to the proximal carrier portion; and

c) wherein the carrier is of a bioresorbable material that is absorbable into body tissue after implantation of the electrode device comprising the carrier and the electrical subsystem, thereby leaving the plurality electrode sites facing outwardly toward the body tissue from the supporting electrode substrate.

37. The implantable electrode device of claim 36 , wherein the electrode substrate has a tubular shape.

38. An implantable electrode device, comprising:

a) a carrier, comprising:

i) a carrier sidewall extending along a carrier length from a proximal carrier portion to a distal carrier portion having a distal carrier end; and

ii) a lumen extending through the carrier along the carrier length from the proximal carrier portion to the distal carrier end;

b) an electrical subsystem, comprising:

i) at least one electrode site;

ii) an electrode substrate supporting the at least one electrode site, wherein at least a portion of the electrode substrate supporting the at least one electrode site is supported by the carrier so that the at least one electrode site has an exposed surface facing outwardly from the electrode substrate opposite the carrier; and

iii) an electrical connector extending from the at least one electrode site to a proximal connector portion adjacent to the proximal carrier portion; and

c) wherein the carrier is of a bioresorbable material that is absorbable into body tissue after implantation of the electrode device comprising the carrier and the electrical subsystem, thereby leaving the at least one electrode site facing outwardly toward the body tissue from the supporting electrode substrate.

39. The implantable electrode device of claim 38 wherein the carrier sidewall has a substantially tubular shape.

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Oct 12, 2022
From: MANUFACTURERS AND TRADERS TRUST COMPANY (AS ADMINISTRATIVE AGENT)
To: GREATBATCH, INC.; GREATBATCH LTD.; ELECTROCHEM SOLUTIONS, INC.; NEURONEXUS TECHNOLOGIES, INC.; GREATBATCH-GLOBE TOOL, INC.; PRECIMED INC.; MICRO POWER ELECTRONICS, INC.
Reel/Frame 061659/0858 →
RELEASE OF SECURITY INTEREST Recorded Jan 6, 2022
From: MANUFACTURERS AND TRADERS TRUST COMPANY (AS ADMINISTRATIVE AGENT)
To: GREATBATCH, INC.; GREATBATCH LTD.; ELECTROCHEM SOLUTIONS, INC.; NEURONEXUS TECHNOLOGIES, INC.; GREATBATCH-GLOBE TOOL, INC.; PRECIMED INC.; MICRO POWER ELECTRONICS, INC.
Reel/Frame 060938/0069 →
RELEASE OF SECURITY INTEREST Recorded Jun 23, 2016
From: MANUFACTURERS AND TRADERS TRUST COMPANY
To: GREATBATCH LTD.; GREATBATCH INC.; QIG GROUP LLC; NEURONEXUS TECHNOLOGIES, INC.; MICRO POWER ELECTRONICS, INC.; ELECTROCHEM SOLUTIONS, INC.
Reel/Frame 039132/0773 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNORS NAME PREVIOUSLY RECORDED ON REEL 037435 FRAME 0512. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 25, 2016
From: GREATBATCH LTD.
To: NEURONEXUS TECHNOLOGIES, INC.
Reel/Frame 037579/0177 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2016
From: GREATBATCH, LTD.
To: NEURONEXUS TECHNOLOGIES, INC.
Reel/Frame 037435/0512 →
SECURITY INTEREST Recorded Oct 27, 2015
From: GREATBATCH, INC.; GREATBATCH LTD.; ELECTROCHEM SOLUTIONS, INC.; NEURONEXUS TECHNOLOGIES, INC.; GREATBATCH-GLOBE TOOL, INC.; PRECIMED INC.; MICRO POWER ELECTRONICS, INC.
To: MANUFACTURERS AND TRADERS TRUST COMPANY
Reel/Frame 036980/0482 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 1, 2015
From: NEURONEXUS TECHNOLOGIES, INC.
To: GREATBATCH LTD.
Reel/Frame 036701/0156 →
GRANT OF SECURITY INTEREST Recorded May 24, 2012
From: NEURONEXUS TECHNOLOGIES, INC.
To: MANUFACTURERS AND TRADERS TRUST COMPANY
Reel/Frame 028274/0763 →