IP Library Granted Patent US 7,601,719
Granted Patent B2
US 7,601,719 · App. 12/254,356 · Granted Oct 13, 2009

Compounds, methods and pharmaceutical compositions for inhibiting PARP

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Quick Facts
Patent No.
US 7,601,719
App. No.
12/254,356
Granted
Oct 13, 2009
Kind
B2
Abstract

The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.

Claims (2)

1. A method of treating cancer in a mammal, wherein the cancer is selected from the group consisting of melanoma, lymphoma, and glioblastoma multiforme, comprising administering to the mammal an effective amount of temozolomide and a compound selected from the group consisting of:

2. A method of claim 1 , wherein the cancer is glioblastoma multiforme.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2010
From: EISAI CORPORATION OF NORTH AMERICA
To: EISAI INC.
Reel/Frame 023796/0776 →