Quick priming connectors for blood circuit

1. A connector system for use in priming a fluid circuit having a pump, a conduit having a first end coupled with the pump and a second end, a cannula having a first end, a second end configured to fluidly couple with a first fluid source, and a cannula lumen extending between the first and second ends of the cannula, the system comprising:

a first connector configured to couple with the second end of the conduit, the first connector comprising a gas permeable membrane, a main lumen extending from the gas permeable membrane, and a secondary lumen having a first end configured to couple with a second fluid source and a second end in fluid communication with the main lumen; and

a second connector configured to couple with the first end of the cannula, the second connector having an end configured to be inserted through the gas permeable membrane into the first connector, whereby fluid communication can be established between the main lumen of the first connector and the cannula lumen;

wherein the first connector comprises a first surface and the end of the second connector comprises a second surface, the first and second surfaces configured to engage to provide a seamless lumen within the first connector at least at the location where the first and second surfaces engage.

2. The connector system of claim 1 , wherein the seamless lumen is provided when the end of the second connector is fully inserted into the first connector.

3. The connector system of claim 1 , wherein the second surface conforms to the first surface when the end of the second connector is fully inserted into the first connector, such that a seal is formed between the first and second surfaces.

4. The connector system of claim 1 , wherein the first fluid source is a source of blood.

5. The connector system of claim 1 , further comprising a second fluid source.

6. The connector system of claim 5 , wherein the second fluid source contains a biocompatible liquid.

7. The connector system of claim 6 , wherein the biocompatible liquid is saline.

8. A connector system for use in priming a fluid circuit, the system comprising:

a first connector having a first end configured to couple with a fluid circuit and a second end comprising a gas permeable membrane, a main lumen extending from the gas permeable membrane to the first end, and a secondary lumen in fluid communication with the main lumen, the secondary lumen having a first end configured to couple with a fluid source and a second end coupled to the main lumen at a location between the gas permeable membrane and the first end of the first connector; and

a second connector configured to couple with the fluid circuit, the second connector having an end configured to be inserted through the gas permeable membrane into the first connector, whereby fluid communication can be established between the main lumen of the first connector and the second connector.

9. The connector system of claim 8 , further comprising:

a conduit having a first end coupled with a pump and a second end configured to couple with the first end of the first connector; and

a cannula having a first end coupled with the second connector and a second end configured to fluidly couple with another fluid source.

10. The connector system of claim 9 , wherein the another fluid source is a source of blood.

11. The connector system of claim 8 , further comprising a fluid source.

12. The connector system of claim 11 , wherein the fluid source comprises a biocompatible liquid.

13. The connector system of claim 12 , wherein the biocompatible liquid is saline.

14. The connector system of claim 8 , wherein:

a portion of the main lumen of the first connector comprises an internal surface that is angled relative to a longitudinal axis of the main lumen and that comprises a distal region and a proximal region; and

the end of the second connector configured to be inserted through the gas permeable membrane comprises a piercing member, the piercing member comprising a tip having an inclined surface that matches the angled internal surface of the portion of the main lumen.

15. A connector system for use in priming a fluid circuit having a conduit with a first end and a second end, a cannula having a first end, a second end configured to fluidly couple with a first fluid source, and a cannula lumen extending between the first and second ends of the cannula, the system comprising:

a first connector configured to couple with the second end of the conduit, the first connector comprising a main lumen and a secondary lumen having a first end configured to couple with a second fluid source and a second end in fluid communication with the main lumen;

a gas permeable membrane removably coupled with the first connector and configured such that the connector system is reusable; and

a second connector configured to couple with the first end of the cannula, the second connector having an end configured to be inserted through the gas permeable membrane into the first connector, whereby fluid communication can be established between the main lumen of the first connector and the cannula lumen.

16. The connector system of claim 15 , further comprising a removable end cap, wherein the membrane is configured to be positioned between the end cap and the first connector.

17. The connector system of claim 16 , wherein the membrane is part of a membrane assembly, the membrane assembly further comprising a seal member configured to be positioned between the end cap and the first connector.

18. The connector system of claim 17 , wherein the seal member is an o-ring.

19. The connector system of claim 15 , wherein the first fluid source is a source of blood.

20. The connector system of claim 15 , further comprising a second fluid source, the second fluid source containing a biocompatible liquid.