IP Library Granted Patent US 8,938,290
Granted Patent B2
US 8,938,290 · App. 12/262,146 · Granted Jan 20, 2015

Systems, methods and devices for a skull/brain interface

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Quick Facts
Patent No.
US 8,938,290
App. No.
12/262,146
Granted
Jan 20, 2015
Kind
B2
Abstract

Systems, methods and devices are disclosed for directing and focusing signals to the brain for neuromodulation and for directing and focusing signals or other energy from the brain for measurement, heat transfer and imaging. An aperture in the skull and/or a channel device implantable in the skull can be used to facilitate direction and focusing. Treatment and diagnosis of multiple neurological conditions may be facilitated with the disclosed systems, methods and devices.

Claims (20)

1. A method for facilitating detection of EEG signals from the brain of a human patient comprising:

facilitating transmission of an ionic current generated by a source in the brain through at least one conduit having a distal end oriented towards the source and a proximal end oriented towards an outer layer of the patient's skull;

wherein the at least one conduit comprises a transcranial channel including an interior cavity at least partially filled with a substance configured to facilitate transmission of the ionic current from the source in the brain toward the outer layer of the patient's skull.

2. The method of claim 1 , further comprising providing a biocompatible coating on at least a portion of the conduit wherein the biocompatible coating is substantially impermeable to ions.

3. The method of claim 1 , wherein the substance permits ionic conduction of direct current.

4. The method of claim 1 , wherein the substance comprises one or more of the following: porous silicone, a porous polyurethane, a saline solution, and a hydrogel.

5. The method of claim 1 , wherein the substance comprises a porous mass constructed by sintering together particles of a nonporous polymer, wherein the nonporous polymer comprises one or more of the following: a polyurethane, a polytetrafluoroethylene, a polyetheretherketone, a polyester, and a polyamide.

6. The method of claim 1 , wherein the substance is provided in an open-pore sponge.

7. A method for facilitating detection of EEG signals from the brain of a human patient comprising:

facilitating transmission of an ionic current generated by a source in the brain through at least one conduit having a distal end oriented towards the source and a proximal end oriented towards an outer layer of the patient's skull;

wherein the at least one conduit comprises a plurality of transcranial channels, each channel including an interior cavity at least partially filled with a substance configured to facilitate transmission of the ionic current from the source in the brain toward the outer layer of the patient's skull.

8. The method of claim 7 , wherein the substance permits ionic conduction of direct current.

9. The method of claim 7 , wherein the substance comprises one or more of the following: porous silicone, a porous polyurethane, a saline solution, and a hydrogel.

10. The method of claim 7 , wherein the substance comprises a porous mass constructed by sintering together particles of a nonporous polymer, wherein the nonporous polymer comprises one or more of the following: a polyurethane, a polytetrafluoroethylene, a polyetheretherketone, a polyester, and a polyamide.

11. The method of claim 7 , wherein the substance is provided in an open-pore sponge.

12. The method of claim 7 , further comprising providing a biocompatible coating on at least a portion of the conduit wherein the biocompatible coating is substantially impermeable to ions.

13. A method for facilitating detection of EEG signals from the brain of a human patient comprising:

facilitating transmission of an ionic current generated by a source in the brain through at least one conduit having a distal end oriented towards the source and a proximal end oriented towards an outer layer of the patient's skull;

wherein the at least one conduit comprises a plurality of inner lumens.

14. The method of claim 13 , further comprising providing a biocompatible coating on at least a portion of the conduit wherein the biocompatible coating is substantially impermeable to ions.

Assignments (5)
SECURITY INTEREST Recorded Jun 25, 2025
From: NEUROPACE, INC.
To: MIDCAP FUNDING IV TRUST
Reel/Frame 071712/0422 →
RELEASE OF SECURITY INTEREST Recorded Jun 4, 2025
From: CRG SERVICING LLC AS SUCCESSOR TO CAPITAL ROYALTY PARTNERS II L.P., CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P., AND PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: NEUROPACE INC.
Reel/Frame 071495/0800 →
SECURITY INTEREST Recorded Sep 25, 2020
From: NEUROPACE, INC.
To: CRG SERVICING LLC
Reel/Frame 053885/0932 →
SHORT-FORM PATENT SECURITY AGREEMENT Recorded Nov 20, 2014
From: NEUROPACE, INC.
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 034410/0767 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 4, 2008
From: WINGEIER, BRETT; PLESS, BENJAMIN
To: NEUROPACE, INC.
Reel/Frame 021784/0936 →