Endoscopic ligation
View Patent ↗A ligature delivery device includes a control member, an elongated shaft, and an end effector attached to the distal end of the elongated shaft. An activation mechanism provides an user-operable connection between the control member and the end effector. In several embodiments, the end effector includes a reverse grasping mechanism. Several embodiments of ligature devices are adapted to be deployed endoscopically and/or translumenally using the reverse-grasping delivery device.
1. A method for ligating tissue, comprising:
providing a device having an elongated flexible shaft and a reverse grasping end effector including a first arm movable relative to a second arm located at or near a distal end of the shaft;
advancing the end effector into the body of a patient to a location of a target tissue;
advancing at least the first arm to a position distal of the target tissue in relation to the flexible shaft;
pivoting the first arm in a first direction by moving an actuator associated with the elongated flexible shaft, such that the end effector forms a tissue engaging shape;
retracting the end effector to engage the target tissue with the tissue engaging shape;
pivoting the first arm further in the first direction to compress the target tissue between the first and second arms, and to deform a ligature positioned between the first and second arms around the target tissue; and
removing the device including the elongated flexible shaft and the reverse grasping end effector from the patient, while leaving the ligature on the target tissue.
2. The method of claim 1 , wherein the actuator is within a lumen of the elongated flexible shaft.
3. The method of claim 1 , wherein the ligature comprises a deformable clip having a first leg on the first arm and a second leg on the second arm.
4. The method of claim 3 further comprising placing a locking ring onto the clip.
5. The method of claim 1 , wherein the end effector is advanced into the body of the patient translumenally.
6. The method of claim 5 , wherein the end effector is advanced into the body of the patient through a natural body orifice.
7. The method of claim 1 , wherein the first arm member is pivotable more than 90 degrees relative to the second arm member.
8. The method of claim 1 , wherein the first arm member is pivotable more than 120 degrees relative to the second arm member.
9. The method of claim 1 , wherein the first arm member is pivotable at least 180 degrees relative to the second arm member.
10. The method of claim 1 , wherein said device further includes a longitudinal channel defined by said flexible shaft, and a second ligature disposed in the longitudinal channel.
11. The method of claim 10 , further comprising deploying said second ligature onto a second target tissue.
12. The method of claim 1 , wherein advancing the end effector into the body of a patient further comprises advancing the end effector through a lumen of an overtube having a plurality of lumens extending therethrough such that the flexible shaft is translatably disposed in a first one of said lumens of said overtube.
13. The method of claim 12 , further comprising advancing an endoscope through a second one of said lumens of said overtube.
14. The method of claim 13 , wherein a distal end of said movable arm is within the field of view of said endoscope.
15. A method for ligating tissue, comprising:
advancing a reverse grasping end effector on the end of an elongated flexible shaft into the body of a patient to a location of target tissue;
advancing a first arm of the end effector to a position past the target;
pivoting the first arm in a first direction to form an acute angle with a second arm on the end effector by pushing or pulling on an actuator linked to at least one of the first and second arms;
retracting the end effector to engage the target tissue with the acute angle between the first and second arms;
pivoting the first arm further in the first direction to simultaneously compress the target tissue and to clamp a ligature onto the target tissue;
pivoting the first arm in a second direction to release the target tissue, with the ligature remaining clamped onto the target tissue; and
removing the reverse grasping end effector from the location.
16. The method of claim 15 with the ligature comprising a clip having first and second clip arms, and with the pivoting of the first arm bending the first and second clip arms onto the target tissue.