Antibodies that bind DNAX leukocyte associated immunoglobulin-like receptor
View Patent ↗Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using reagents and related diagnostic kits are also provided.
1. An isolated or purified antibody, or antigen binding portion thereof, that specifically binds to a polypeptide comprising amino acid residues 1-266 of SEQ ID NO: 6.
2. The antibody, or antigen binding portion thereof, of claim 1 , wherein said antibody is a monoclonal antibody.
3. The monoclonal antibody, or antigen binding portion thereof, of claim 2 , wherein said monoclonal antibody is humanized.
4. The antibody of claim 1 , wherein said antibody, or antigen binding portion thereof, is a single chain antibody.
5. The antibody, or antigen binding portion thereof, of claim 1 , wherein said antibody or antigen binding portion thereof is a Fv, Fab, or F(ab′)2 antibody fragment.
6. A kit comprising:
a) the antibody, or antigen binding fragment thereof, of claim 1 ; and
b) instructions for use.
7. A composition comprising an antibody, or antigen binding portion thereof, of claim 1 in a sterile form.
8. A composition comprising an antibody, or antigen binding portion thereof, of claim 1 and a carrier, wherein said carrier is water, saline, or buffer.
9. An isolated or purified antibody, or antigen binding portion thereof, that specifically binds to a polypeptide comprising amino acid residues 1-114 of SEQ ID NO: 10.
10. The antibody, or antigen binding portion thereof, of claim 9 , wherein said antibody is a monoclonal antibody.
11. The monoclonal antibody, or antigen binding portion thereof, of claim 10 , wherein said monoclonal antibody is humanized.
12. The antibody of claim 9 , wherein said antibody, or antigen binding portion thereof, is a single chain antibody.
13. The antibody or antigen binding portion thereof, of claim 9 , wherein said antibody or antigen binding portion thereof is a Fv, Fab, or F(ab′)2 antibody fragment.
14. A kit comprising:
a) the antibody, or antigen binding fragment thereof, of claim 9 ; and
b) instructions for use.
15. A composition comprising an antibody, or antigen binding portion thereof, of claim 9 in a sterile form.
16. A composition comprising an antibody, or antigen binding portion thereof, of claim 9 and a carrier, wherein said carrier is water, saline, or buffer.
17. An isolated or purified antibody, or antigen binding portion thereof, that specifically binds to a polypeptide comprising amino acid residues 1-266 of SEQ ID NO: 8.
18. The antibody, or antigen binding portion thereof, of claim 17 , wherein said antibody is a monoclonal antibody.
19. The monoclonal antibody, or antigen binding portion thereof, of claim 18 , wherein said monoclonal antibody is humanized.
20. The antibody of claim 17 , wherein said antibody, or antigen binding portion thereof, is a single chain antibody.
21. The antibody or antigen binding portion thereof, of claim 17 , wherein said antibody or antigen binding portion thereof is a Fv, Fab, or F(ab′)2 antibody fragment.
22. A kit comprising:
a) the antibody, or antigen binding fragment thereof, of claim 17 ; and
b) instructions for use.
23. A composition comprising an antibody, or antigen binding portion thereof, of claim 17 , in a sterile form.
24. A composition comprising an antibody, or antigen binding portion thereof, of claim 17 and a carrier, wherein said carrier is water, saline, or buffer.