IP Library Granted Patent US 7,980,698
Granted Patent B2
US 7,980,698 · App. 12/273,720 · Granted Jul 19, 2011

Power-adjusted aberrometer

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Quick Facts
Patent No.
US 7,980,698
App. No.
12/273,720
Granted
Jul 19, 2011
Kind
B2
Abstract

Aspects of the invention are directed to apparatus and methods for automatically setting a power level of light emitted by a light source; illuminating a retina of a patient with the light emitted by the light source; receiving, at a sensor, light reflected from the retina of the patient; providing a signal based upon the received light; determining whether the signal meets one or more signal quality criteria; automatically setting a second power level of light emitted by the light source; and repeating the steps of illuminating the patient's eye, receiving reflected light, providing the signal, and determining whether the signal meets the signal quality criteria. In some embodiments, setting the second power level is performed in response to determining whether the signal meets the signal criteria. In still other embodiments, the method comprises selecting an operating power based upon the signal quality criteria.

Claims (131)

1. A method comprising:

setting automatically a first power level of light emitted by a light source;

illuminating a retina of a patient with the light emitted by the light source;

receiving, at a sensor, light reflected from the retina of the patient;

providing a signal based upon the received light;

determining whether the signal meets one or more signal quality criteria;

setting automatically a second power level of light emitted by the light source in response to the determining whether the signal meets one or more signal quality criteria; and

repeating illuminating, receiving, providing, and determining

wherein determining whether the signal meets one or more signal quality criteria comprises:

identifying a plurality of peak signal levels within the signal;

determining a number of peak signal levels that are not less than a first predetermined value; and

determining whether the number is not less than a redetermined number.

2. The method of claim 1 , wherein repeating further comprises repeating until the signal meets the one or more signal quality criteria.

3. The method of claim 1 , wherein determining whether the signal meets one or more signal quality criteria further comprises:

identifying a background signal level, wherein the first predetermined value is a predetermined value by which the peak signal level exceeds the background level;

and the step of determining a number of peak signal levels comprises determining a number of peak signal levels that exceed the background signal level by at least a predetermined value.

4. The method of claim 1 , wherein

the step of determining a number of peak signal levels comprises determining a number of peak signal levels that fall between a first predetermined value and a second predetermined value.

5. The method of claim 1 , wherein determining whether the signal meets one or more signal quality criteria further comprises:

identifying a background signal level;

determining, for each of the plurality of peak signal levels, a signal-to-noise ratio;

determining a number of signal-to-noise ratios that are not less than a predetermined value.

6. A method comprising:

setting automatically a first power level of light emitted by a light source;

illuminating a retina of a patient with the light emitted by the light source;

receiving, at a sensor, light reflected from the retina of the patient;

providing a signal based upon the received light;

determining whether the signal meets one or more signal quality criteria;

setting automatically a second power level of light emitted by the light source in response to the determining whether the signal meets one or more signal quality criteria; and

repeating illuminating, receiving, providing, and determining wherein the signal comprises a plurality of signal levels, and

wherein determining whether the signal meets one or more signal quality criteria further comprises:

generating a histogram of at least a portion of the plurality of signal levels;

identifying, in the histogram, a peak corresponding to a subset of the plurality of the signal levels comprising signal levels distinguishable from a background signal level; and

determining whether a number of signal levels in the peak is not less than a predetermined value.

7. A method comprising:

setting automatically a first power level of light emitted by a light source;

illuminating a retina of a patient with the light emitted by the light source;

receiving, at a sensor, light reflected from the retina of the patient;

providing a signal based upon the received light;

determining whether the signal meets one or more signal quality criteria;

setting automatically a second power level of light emitted by the light source in response to the determining whether the signal meets one or more signal quality criteria; and

repeating illuminating, receiving, providing, and determining

wherein:

the sensor comprises a plurality of elements; and

the signal comprises a plurality of signal levels, each signal level corresponding to one of the plurality of elements of the sensor; and wherein determining whether the signal meets one or more signal quality criteria further comprises:

determining, for each of the plurality of sensor elements, whether a signal at the sensor element is saturated;

determining a number of sensor elements at which the signal at the sensor element is saturated; and

determining whether the number is not greater than a predetermined number.

8. The method of claim 1 , wherein determining whether the signal meets one or more signal quality criteria further comprises:

generating a Fourier transform of at least a portion of the signal;

determining a signal-to-noise ratio of at least a portion of the Fourier transform of the signal; and

determining whether the signal-to-noise ratio is not less than a predetermined value.

9. The method of claim 1 , wherein:

the sensor further comprises an array of sensor elements;

receiving further comprises receiving at the array of sensor elements light reflected from the retina of the patient through an array of lenslets; and

providing the signal further comprises providing a signal indicative of the optical power received at each of the sensor elements of the array of sensor elements.

10. The method of claim 9 , wherein determining whether the signal meets one or more signal quality criteria further comprises:

determining a plurality of center positions in the signal, each center position corresponding to one of the lenslets in the array of lenslets;

determining an uncertainty in the center position for each of the plurality of center positions;

determining a number of center positions having uncertainties that are not greater than a predetermined uncertainty value; and

determining whether the number is not less than a predetermined number.

11. The method of claim 1 , wherein setting the power level of the light emitted by the light source comprises setting a power control signal of the light source.

12. The method of claim 11 , wherein setting the power control signal of the light source comprises setting the power control signal of the light source by pulse-width modulation.

13. The method of claim 1 , wherein setting the power level of the light emitted by the light source comprises setting the attenuation of a filter in a beam path of the light emitted by the light source.

14. The method of claim 1 , further comprising:

selecting an operating power based upon the signal quality criteria.

15. An apparatus comprising:

a light source adapted to illuminate a patient's retina;

a sensor adapted to receive light reflected from the patient's retina and to provide a signal based upon the received light; and

a processor coupled to the sensor and adapted to:

set a first power level of light emitted by the light source;

receive the signal provided by the sensor;

process the signal to determine whether the signal meets one or more signal quality criteria;

set a second power level of light emitted by the light source in response to determining whether the signal meets one or more signal criteria; and

repeat receiving the signal and processing the signal

wherein the processor is further adapted to:

identify a plurality of peak signal levels within the signal;

determine a number of peak signal levels that are not less than a first predetermined value; and

determine whether the number is not less than a predetermined number.

16. The apparatus of claim 15 , wherein the processor is further adapted to repeat receiving the signal and processing the signal until the signal meets the one or more signal quality criteria.

17. The apparatus of claim 15 , wherein the processor is further adapted to:

identify a background signal level, wherein the first predetermined value is a predetermined value by which the peak signal level exceeds the background level, and wherein the adaptation of the processor to determine a number of peak signal levels comprises the processor being adapted to determine a number of peak signal levels that exceed the background signal level by at least a predetermined value.

18. The apparatus of claim 15 , wherein

the adaptation of the processor to determine a number of peak signal levels comprises the processor being adapted to determine a number of peak signal levels that fall between a first predetermined value and a second predetermined value.

19. The apparatus of claim 15 , wherein the processor is further adapted to:

identify a background signal level;

determine, for each of the plurality of peak signal levels, a signal-to-noise ratio;

determine a number of signal-to-noise ratios that are not less than a predetermined value; and

determine whether the number is not less than a predetermined number.

20. An apparatus comprising:

a light source adapted to illuminate a patient's retina;

a sensor adapted to receive light reflected from the patient's retina and to provide a signal based upon the received light; and

a processor coupled to the sensor and adapted to:

set a first power level of light emitted by the light source;

receive the signal provided by the sensor;

process the signal to determine whether the signal meets one or more signal quality criteria;

set a second power level of light emitted by the light source in response to determining whether the signal meets one or more signal criteria; and

repeat receiving the signal and processing the signal wherein the signal comprises a plurality of signal levels, and wherein the processor is further adapted to:

generate a histogram of at least a portion of the plurality of signal levels;

identify, in the histogram, a peak corresponding to a subset of the plurality of the signal levels comprising signal levels distinguishable from a background signal level; and

determine whether a number of signal levels in the peak is not less than a predetermined value.

21. An apparatus comprising:

a light source adapted to illuminate a patient's retina;

a sensor adapted to receive light reflected from the patient's retina and to provide a signal based upon the received light; and

a processor coupled to the sensor and adapted to:

set a first power level of light emitted by the light source;

receive the signal provided by the sensor;

process the signal to determine whether the signal meets one or more signal quality criteria;

set a second power level of light emitted by the light source in response to determining whether the signal meets one or more signal criteria; and repeat receiving the signal and processing the signal wherein:

the sensor comprises a plurality of elements; and

the signal comprises a plurality of signal levels, each signal level corresponding to one of the plurality of elements of the sensor; and wherein the processor is further adapted to:

determine, for each of the plurality of sensor elements, whether a signal at the sensor element is saturated;

determine a number of sensor elements at which the signal at the sensor element is saturated; and

determine whether the number is not greater than a predetermined number.

22. The apparatus of claim 15 , wherein the processor is further adapted to:

generate a Fourier transform of at least a portion of the signal;

determine a signal-to-noise ratio of at least a portion of the Fourier transform of the signal; and

determine whether the signal-to-noise ratio is not less than a predetermined value.

23. The apparatus of claim 15 , further comprising an array of lenslets, wherein:

the sensor comprises an array of sensor elements;

the sensor is further adapted to receive the light reflected from the patient's retina through the array of lenslets; and

the signal based upon the received light is indicative of the optical power received at each of the sensor elements of the array of sensor elements.

24. The apparatus of claim 23 , wherein the processor is further adapted to:

determine a plurality of center positions in the signal, each center position corresponding to one of the lenslets in the array of lenslets;

determine an uncertainty in the center position for each of the plurality of center positions;

determine a number of center positions having uncertainties that are not greater than a predetermined uncertainty value; and

determine whether the number is not less than a predetermined number.

25. The apparatus of claim 15 , wherein the processor is further adapted to set a power control signal of the light source.

26. The apparatus of claim 25 , wherein the processor is further adapted to set the power control signal of the light source by pulse-width modulation.

27. The apparatus of claim 15 , the apparatus further comprising a light attenuation filter disposed in a beam path of the light emitted by the light source, wherein the processor is further adapted to set an attenuation of the light attenuation filter.

28. The apparatus of claim 15 , wherein the processor is further adapted to select an operating power based upon the signal quality criteria.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Apr 8, 2025
From: BARCLAYS BANK PLC, AS COLLATERAL AGENT
To: SOLTA MEDICAL, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED); SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD; SANTARUS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; HUMAX PHARMACEUTICAL S.A.; SOLTA MEDICAL IRELAND LIMITED; BAUSCH & LOMB MEXICO, S.A. DE C.V.; BAUSCH+LOMB OPS B.V.; BAUSCH HEALTH AMERICAS, INC.; BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH HOLDCO LIMITED; BAUSCH HEALTH MAGYARORSZAG KFT (A/K/A BAUSCH HEALTH HUNGARY LLC); BAUSCH HEALTH POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (F/K/A VALEANT PHARMA POLAND SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA); BAUSCH HEALTH US, LLC; BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC.; ICN POLFA RZESZOW SPOLKA AKCYJNA (A/K/A ICN POLFA RZESZOW S.A.); ORAPHARMA, INC.; PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.); SOLTA MEDICAL DUTCH HOLDINGS B.V.; V-BAC HOLDING CORP.; VRX HOLDCO LLC; 1261229 B.C. LTD.; 1530065 B.C. LTD.
Reel/Frame 070778/0199 →
NOTICE OF SUCCESSION OF AGENCY Recorded Jan 9, 2015
From: GOLDMAN SACHS LENDING PARTNERS, LLC
To: BARCLAYS BANK PLC, AS SUCCESSOR AGENT
Reel/Frame 034749/0689 →
SECURITY AGREEMENT Recorded Sep 4, 2013
From: BAUSCH & LOMB INCORPORATED
To: GOLDMAN SACHS LENDING PARTNERS LLC, AS COLLATERAL AGENT
Reel/Frame 031156/0508 →
RELEASE OF SECURITY INTEREST Recorded Aug 13, 2013
From: CITIBANK N.A., AS ADMINISTRATIVE AGENT
To: WP PRISM INC. (N/K/A BAUSCH & LOMB HOLDINGS INC.); BAUSCH & LOMB INCORPORATED; ISTA PHARMACEUTICALS
Reel/Frame 030995/0444 →
SECURITY AGREEMENT Recorded Aug 6, 2012
From: BAUSCH & LOMB INCORPORATED; EYEONICS, INC.
To: CITIBANK N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 028728/0645 →
RELEASE OF SECURITY INTEREST Recorded Aug 5, 2012
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: BAUSCH & LOMB INCORPORATED
Reel/Frame 028726/0142 →
SECURITY AGREEMENT Recorded Aug 15, 2011
From: BAUSCH & LOMB INCORPORATED
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Reel/Frame 026753/0554 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2011
From: EAGAN, BARRY
To: BAUSCH & LOMB INCORPORATED
Reel/Frame 026118/0321 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 19, 2008
From: ALLRED, LLOYD G.; MCBETH, JEFFREY B.
To: BAUSCH & LOMB INCORPORATED
Reel/Frame 021858/0618 →