IP Library Granted Patent US 7,760,924
Granted Patent B2
US 7,760,924 · App. 12/276,006 · Granted Jul 20, 2010

System and method for generating a 2D image from a tomosynthesis data set

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Quick Facts
Patent No.
US 7,760,924
App. No.
12/276,006
Granted
Jul 20, 2010
Kind
B2
Abstract

A 2D mammogram image is synthesized from at least one of tomosynthesis projection images and/or the tomosynthesis reconstructed image data. In a simplest form, the mammogram may be synthesized by selecting one of the tomosynthesis projection images for display as a synthesized mammogram. Other methods of synthesizing a mammogram include re-projecting and filtering projection data and/or reconstructed data. The synthesized mammogram is advantageously displayed together with at least a portion of the reconstructed data to aid in review of the reconstructed data. The present invention thus provides a familiar image which may be used to facilitate review of a tomosynthesis data set.

Claims (29)

1. A method for use in a computer system comprising one or more processors performing the steps of:

obtaining a plurality of x-ray tomosynthesis projection images of a patient's breast;

generating a three dimensional reconstruction of the patient's breast using the x-ray projection images;

synthesizing a two-dimensional mammogram using at least a subset of the plurality of x-ray tomosynthesis projection images, including re-projecting at least a portion of the three dimensional reconstruction onto a two-dimensional image; and

displaying the synthesized mammogram on a display device.

2. The method of claim 1 wherein the step of synthesizing the two dimensional mammogram includes the step of selecting one of the x-ray tomosynthesis projection images for use as the two-dimensional mammogram.

3. The method of claim 1 wherein the step of synthesizing the two dimensional mammogram includes the step of performing at least one of filtering and combining of a subset of the plurality of x-ray tomosynthesis images.

4. The method of claim 1 including the step of displaying the synthesized mammogram together with at least a portion of the three-dimensional reconstruction.

5. The method of claim 1 wherein the synthesized mammogram and at least a portion of the three-dimensional reconstruction are displayed overlaid to enable toggling between the synthesized mammogram and the portion of the three-dimensional reconstruction.

6. The method of claim 1 including the step of providing a user interface for controlling the display of at least one of a portion of the three dimensional reconstruction, at least one of the x-ray projection images and the mammogram.

7. The method of claim 1 wherein the synthesized mammogram is matched in size and shape with the portion of the three dimensional reconstruction.

8. The method of claim 1 wherein the synthesized mammogram is displayed as a scout view.

9. The method of claim 1 wherein the synthesized mammogram is generated in response to a selection of a mammogram view at a user interface of a tomosynthesis system coupled to the display device.

10. The method of claim 1 including the step of retrieving a legacy mammogram from a storage device and displaying the legacy mammogram together with the synthesized mammogram on a display device.

11. The method of claim 1 wherein the tomosynthesis projection images are retrieved from a storage device coupled to a mammography system that includes the display device, and wherein the synthesized mammogram is displayed for comparison against a mammogram obtained by the mammography system.

12. The method of claim 1 wherein the x-ray tomosynthesis projection images are obtained by a dedicated tomosynthesis system that includes the display device and wherein the synthesized mammogram is displayed with at least one of the tomosynthesis projection images and a portion of a three-dimensional reconstructed tomosynthesis image.

13. The method of claim 1 wherein the x-ray tomosynthesis projection images are obtained by a combination mammography tomosynthesis system that includes the display device.

14. A system comprising:

a processor coupled to a computer readable medium having program code stored thereon, the program code being operable when executed upon by the processor to synthesize an x-ray mammogram using only one or more x-ray tomosynthesis projection images; and

a display device for displaying the synthesized mammogram wherein the program code for synthesizing the mammogram using the x-ray tomosynthesis projection images includes program code for generating a three dimensional reconstruction using the x-ray projection images, and wherein the program code for synthesizing the mammogram performs at least one of filtering and re-projecting of at least one of the x-ray tomosynthesis images and a portion of the three dimensional reconstruction to synthesize the mammogram.

15. The system of claim 14 , wherein the program code for synthesizing the mammogram using the x-ray tomosynthesis projection images selects one of the x-ray tomosynthesis projection images for display on the display device.

16. The system of claim 15 wherein the program code for synthesizing the mammogram uses a tomosynthesis projection image taken when the x-ray source is normal to the digital detector.

17. A system comprising:

a processor coupled to a computer readable medium having program code stored thereon, the program code being operable when executed upon by the processor to synthesize an x-ray mammogram using only one or more x-ray tomosynthesis projection images; and

a display device for displaying the synthesized mammogram; and

an image acquisition device for obtaining the x-ray tomosynthesis projection images, the image acquisition device comprising an x-ray source, a digital detector and a controller;

wherein the program code is further operable when executed upon by the processor to reconstruct the tomosynthesis projection images into a three dimensional reconstructed image for synthesizing the mammogram and for generating a set of slabbed slices from the reconstructed image, re-projecting the set of slabbed slices to provide a two dimensional image and filtering the two dimensional image to provide the synthesized mammogram.

18. The system of claim 17 further comprising:

a storage device for storing the plurality of tomosynthesis projection images.

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
TERMINATION OF PATENT SECURITY AGREEMENTS AND RELEASE OF SECURITY INTERESTS Recorded Aug 26, 2010
From: GOLDMAN SACHS CREDIT PARTNERS, L.P., AS COLLATERAL AGENT
To: HOLOGIC, INC.; R2 TECHNOLOGY, INC.; SUROS SURGICAL SYSTEMS, INC.; BIOLUCENT, LLC; DIRECT RADIOGRAPHY CORP.; CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP; CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS III, INC.; CYTYC PRENATAL PRODUCTS CORP.; THIRD WAVE TECHNOLOGIES, INC.
Reel/Frame 024892/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2009
From: RUTH, CHRISTOPHER; SMITH, ANDREW; STEIN, JAY
To: HOLOGIC INC.
Reel/Frame 022126/0621 →