IP Library Granted Patent US 9,889,298
Granted Patent B2
US 9,889,298 · App. 12/281,075 · Granted Feb 13, 2018

Electrode sling for treating stress and urge incontinence

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Quick Facts
Patent No.
US 9,889,298
App. No.
12/281,075
Granted
Feb 13, 2018
Kind
B2
Abstract

Apparatus is provided, including an implantable mechanical support comprising a mesh shaped to support a portion of a urethra of a patient. One or more electrodes, coupled to the mesh, so as to contact tissue of the patient when the mechanical support ( 26 ) is implanted in the patient. A control unit drives the electrodes to apply a current to the tissue. Other embodiments are also described.

Claims (25)

1. An implantable pelvic treatment apparatus, comprising:

an implantable mechanical support comprising mesh shaped to support a portion of a urethra of a patient;

three or more electrodes, coupled to the mechanical support;

one or more circuitry units on the mechanical support; and

a control unit electrically coupled to the one or more circuitry units;

wherein the one or more circuitry units are configured to direct a current from the control unit to a subset of the electrodes in response to a signal from the control unit.

2. The apparatus according to claim 1 , wherein the mechanical support comprises mesh that is shaped to define a longitudinal axis thereof, and wherein all of the electrodes are greater than 2 mm from a center point of the longitudinal axis.

3. The apparatus according to claim 1 , wherein the control unit is operative to configure the treatment current to stimulate a pelvic muscle of the patient and induce contraction of the muscle.

4. The apparatus according to claim 1 , wherein the control unit is operative to configure the treatment current to induce in a nerve of the patient action potential propagation that induces contraction of a pelvic muscle of the patient.

5. The apparatus according to claim 1 , wherein the control unit is operative to configure the treatment current to induce in a nerve of the patient action potential propagation that induces relaxation of a pelvic muscle of the patient.

6. The apparatus according to claim 1 , wherein the mechanical support comprises a sling.

7. The apparatus according to claim 1 , wherein the mechanical support comprises a plurality of beads selected from the group consisting of: carbon beads, and polymer beads.

8. The apparatus according to claim 1 , wherein the mechanical support comprises an electrode lead, and wherein the electrode lead couples the control unit to at least one of the electrodes.

9. The apparatus according to claim 1 , wherein the control unit is wirelessly coupled to the one or more electrodes.

10. The apparatus according to claim 1 , wherein the control unit comprises a drug and a pump operative to pump the drug from the control unit after implantation in the patient.

11. The apparatus according to claim 1 , wherein the pelvic condition is selected from the group consisting of urge incontinence and stress incontinence.

12. The apparatus according to claim 1 , wherein the pelvic condition is selected from the group consisting of: bladder dysfunction, mixed incontinence, overactive bladder, interstitial cystitis, and fecal incontinence.

13. The apparatus according to claim 1 , wherein the control unit is operative to set a frequency of the treatment current to be between 5 and 15 Hz.

14. The apparatus according to claim 1 , wherein the control unit is operative to set a duration of pulses of the treatment current to be between 50 μs and 1 ms.

15. The apparatus according to claim 1 , wherein the control unit is operative to set a pulse duration of pulses of the treatment current to be greater than 1 ms.

16. The apparatus according to claim 1 , comprising a sensor operative to generate a signal indicative of imminent stress incontinence.

17. A method of treating a pelvic condition of a patient comprising:

supporting a portion of a urethra of a patient comprising implanting a mechanical support comprising mesh in the patient; and

selectively driving a current from a control unit through a subset of three or more electrodes attached to the mechanical support in response to a signal from the control unit using one or more circuitry units on the mechanical support; and

treating the pelvic condition in response to selectively driving the current.

Assignments (16)
SECURITY INTEREST Recorded Jul 22, 2024
From: ENDO BIOLOGICS LIMITED; ENDO OPERATIONS LIMITED
To: COMPUTERSHARE TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 068469/0001 →
SECURITY INTEREST Recorded Jul 19, 2024
From: ENDO BIOLOGICS LIMITED; ENDO OPERATIONS LIMITED
To: GOLDMAN SACHS BANK USA
Reel/Frame 068461/0692 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 27, 2024
From: ENDO USA, INC.
To: ENDO OPERATIONS LIMITED
Reel/Frame 067245/0492 →
RELEASE OF SECURITY INTEREST Recorded Apr 26, 2024
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: ACTIENT PHARMACEUTICALS LLC; ASTORA WOMEN’S HEALTH HOLDINGS, LLC; ASTORA WOMEN’S HEALTH LLC; AUXILIUM PHARMACEUTICALS, LLC; AUXILIUM US HOLDINGS, LLC; BIOSPECIFICS TECHNOLOGIES CORP.; BIOSPECIFICS TECHNOLOGIES LLC; DAVA INTERNATIONAL, LLC; DAVA PHARMACEUTICALS, LLC; ENDO GENERIC HOLDINGS, INC. (FORMERLY KNOWN AS PAR PHARMACEUTICALS COMPANIES, INC.); ENDO PHARMACEUTICALS INC.; ENDO PHARMACEUTICALS SOLUTIONS INC. (FORMERLY KNOWN AS INDEVUS PHARMACEUTICALS, INC.); GENERICS BIDCO I, LLC; GENERICS INTERNATIONAL (US), INC.; PAR PHARMACEUTICAL, INC.; PAR STERILE PRODUCTS, LLC (FORMERLY KNOWN AS JHP PHARMACEUTICALS, LLC); QUARTZ SPECIALTY PHARMACEUTICALS, LLC; SLATE PHARMACEUTICALS, LLC; VINTAGE PHARMACEUTICALS, LLC
Reel/Frame 067240/0001 →
RELEASE OF SECURITY INTEREST Recorded Apr 25, 2024
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: ACTIENT PHARMACEUTICALS LLC; ASTORA WOMEN’S HEALTH LLC; AUXILIUM PHARMACEUTICALS, LLC; AUXILIUM US HOLDINGS, LLC; BIOSPECIFICS TECHNOLOGIES CORP.; BIOSPECIFICS TECHNOLOGIES LLC; DAVA INTERNATIONAL, LLC; DAVA PHARMACEUTICALS, LLC; ENDO PHARMACEUTICALS INC.; ENDO PHARMACEUTICALS SOLUTIONS INC. (FORMERLY KNOWN AS INDEVUS PHARMACEUTICALS, INC.); GENERICS BIDCO I, LLC; GENERICS INTERNATIONAL (US), INC.; PAR PHARMACEUTICAL, INC.; PAR PHARMACEUTICAL COMPANIES, INC.; PAR STERILE PRODUCTS, LLC (FORMERLY KNOWN AS JHP PHARMACEUTICALS, LLC); QUARTZ SPECIALTY PHARMACEUTICALS, LLC; SLATE PHARMACEUTICALS, LLC; VINTAGE PHARMACEUTICALS, LLC
Reel/Frame 067239/0491 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 23, 2024
From: ASTORA WOMEN’S HEALTH, LLC
To: ENDO USA, INC.
Reel/Frame 067202/0768 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Sep 17, 2021
From: ASTORA WOMEN'S HEALTH LLC; ENDO PHARMACEUTICALS SOLUTIONS INC.; ENDO PHARMACEUTICALS INC.; PAR PHARMACEUTICAL, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 057538/0978 →
SECURITY INTEREST Recorded Jun 8, 2017
From: ASTORA WOMEN'S HEALTH, LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL TRUSTEE
Reel/Frame 042743/0278 →
CHANGE OF NAME Recorded May 11, 2016
From: AMS RESEARCH CORPORATION
To: AMS RESEARCH, LLC
Reel/Frame 038676/0053 →
CHANGE OF NAME Recorded May 11, 2016
From: APHRODITE WOMEN'S HEALTH, LLC
To: ASTORA WOMEN'S HEALTH, LLC
Reel/Frame 038676/0084 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2016
From: AMS RESEARCH, LLC
To: APHRODITE WOMEN'S HEALTH, LLC
Reel/Frame 038676/0109 →
RELEASE OF SECURITY INTEREST Recorded Aug 6, 2015
From: DEUTSCHE BANK AG NEW YORK BRANCH
To: AMERICAN MEDICAL SYSTEMS, LLC; AMS RESEARCH, LLC; LASERSCOPE
Reel/Frame 036285/0146 →
GRANT OF SECURITY INTEREST IN PATENTS Recorded Mar 20, 2014
From: ENDO PHARMACEUTICALS SOLUTIONS, INC.; ENDO PHARMACEUTICALS, INC.; AMS RESEARCH CORPORATION; AMERICAN MEDICAL SYSTEMS, INC.; LASERSCOPE
To: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
Reel/Frame 032491/0440 →
RELEASE OF PATENT SECURITY INTEREST Recorded Mar 3, 2014
From: MORGAN STANLEY SENIOR FUNDING, INC., AS ADMINISTRATIVE AGENT
To: AMS RESEARCH CORPORATION
Reel/Frame 032380/0053 →
SECURITY AGREEMENT Recorded Jul 22, 2011
From: AMS RESEARCH CORPORATION
To: MORGAN STANLEY SENIOR FUNDING, INC., AS ADMINISTRATIVE AGENT
Reel/Frame 026632/0535 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 20, 2008
From: LONGHINI, ROSS A.; GROSS, YOSEF
To: AMS RESEARCH CORPORATION
Reel/Frame 021705/0338 →