IP Library Granted Patent US 8,071,649
Granted Patent B2
US 8,071,649 · App. 12/283,119 · Granted Dec 6, 2011

Method for treatment of nocturia

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Quick Facts
Patent No.
US 8,071,649
App. No.
12/283,119
Granted
Dec 6, 2011
Kind
B2
Abstract

A method for treatment of nocturia by administering to a mammal, such as a human, in need of such treatment, a therapeutically effective amount of loxoprofen or a pharmacologically acceptable salt thereof.

Claims (10)

1. A method for the treatment of nocturia which consists of administering to a mammal in need of such treatment a therapeutically effective amount of a nonsteroidal anti-inflammatory drug consisting of loxoprofen or a pharmacologically acceptable salt thereof.

2. The method according to claim 1 , wherein loxoprofen or a pharmacologically acceptable salt thereof is loxoprofen.

3. The method according to claim 1 , wherein the mammal is a human.

4. The method according to claim 2 , wherein the mammal is a human.

5. The method according to claim 1 , wherein the mammal is a human whose frequency of nocturia at baseline is 3 or more voids/night and the number of voids per night is reduced by 1 or more times in more than 77% of the humans after the treatment, and wherein the administration is once daily.

6. The method according to claim 1 , wherein the mammal is a human whose frequency of nocturia at baseline is 3 to 5 voids/night and the number of voids per night is reduced by 1 or more times in more than 78% of the humans after the treatment, and wherein the administration is once daily.

7. A method for the treatment of nocturia which consists of administering to a mammal in need of such treatment a therapeutically effective amount of a nonsteroidal anti-inflammatory drug consisting of a pharmacologically acceptable sodium salt of loxoprofen.

8. The method according to claim 7 , wherein the mammal is a human.

9. The method according to claim 7 , wherein the mammal is a human whose frequency of nocturia at baseline is 3 or more voids/night and the number of voids per night is reduced by 1 or more times in more than 77% of the humans after the treatment, and wherein the administration is once daily.

10. The method according to claim 7 , wherein the mammal is a human whose frequency of nocturia at baseline is 3 to 5 voids/night and the number of voids per night is reduced by 1 or more times in more than 78% of the humans after the treatment, and wherein the administration is once daily.

Assignments (2)
MERGER Recorded Apr 27, 2011
From: SANKYO COMPANY, LIMITED
To: DAIICHI SANKYO COMPANY, LIMITED
Reel/Frame 026186/0663 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 9, 2008
From: ARAKI, TOHRU
To: SANKYO COMPANY, LIMITED
Reel/Frame 021567/0064 →