Methods and systems for treating disease
Methods and systems described herein are applicable to the identification of pathogens, pathogenic variants and applicable treatments or remedies. In some embodiments, the pathogen or pathogens bears a causal relationship to a disease state.
1 .- 47 . (canceled)
48 . A system comprising:
a computer program product for use with a computer system and wherein the computer program includes a plurality of instructions including but not limited to;
a set of instructions for identifying at least one primary pathogen associated with a disease state;
a set of instructions for predicting at least one pathogenic variant of a primary pathogen; and
a set of instructions for identifying at least one second treatment targeting at least one predicted pathogenic variant.
49 . The system of claim 48 , further comprising:
a set of instructions for identifying at least one first treatment targeting the primary pathogen associated with a given disease state.
50 . The system of claim 49 comprising:
a set of instructions for predicting the response of the primary pathogen to at least one first treatment.
51 . The system of claim 49 comprising:
a set of instructions for predicting the response of at least one pathogenic variant to at least one first treatment.
52 . The system of claim 49 comprising:
a set of instructions for predicting the response of at least one pathogenic variant to the second treatment.
53 . The system of claim 49 comprising:
a set of instructions for predicting the response of the combination of the primary pathogen and at least one pathogenic variant to the combination of at least one first and at least one second treatment.
54 . The system of claim 48 comprising:
a set of instructions referencing a database.
55 . The system of claim 54 wherein the database comprises known pathogens.
56 . The system of claim 54 wherein the database comprises known disease states.
57 . The system of claim 54 wherein the database comprises known or predicted variants of pathogens.
58 . The system of claim 54 wherein the database comprises molecular structures of pathogens.
59 . The system of claim 48 wherein a plurality of pathogenic variants are predicted.
60 . The system of claim 48 wherein a plurality of second treatments are identified.
61 . The system of claim 48 wherein the pathogen is a virus, a bacterium, a yeast, a mold, a fungus, a mycoplasma , a ureaplasma, a chlamydia , a rickettsia , a nanobacterium, a prion, an agent responsible for a transmissible spongiform encephalopathy (TSE), a multicellular parasite, a protein, an infectious protein, a nucleic acid, a metabolic by-product, a cellular by-product, or a toxin.
62 .- 77 . (canceled)
78 . A system comprising:
a computer program product for use with a computer system and wherein the computer program includes a plurality of instructions including but not limited to:
one or more instructions for identifying at least one pathogen associated with a disease state;
one or more instructions for predicting at least one pathogenic variant of at least one pathogen;
one or more instructions for identifying at least one second treatment targeting at least one predicted pathogenic variant; and
one or more instructions for designating at least one group of pathogenic variants.
79 . The system of claim 78 wherein the one or more instructions for designating at least one group includes at least one reference to at least one user chosen parameter.
80 . The system of claim 79 wherein the user chosen parameter includes at least one of the following; geographic location, a temporal variable, the route of transmission of at least one pathogen, the species of the individual or individuals affected by the disease state, the gender of the individual or individuals affected by the disease state, the age of the individual or individuals affected by the disease state or the results of laboratory testing involving at least one pathogen.
81 . The system of claim 78 wherein the one or more instructions for designating at least one group includes at least one reference to a database.
82 . The system of claim 78 wherein at least one pathogen is associated with a disease state in at least one of: a human, a domestic animal, or a non-domestic animal.
83 . The system of claim 78 , comprising:
one or more instructions for identifying at least one first treatment targeting at least one pathogen associated with a disease state.
84 . The system of claim 78 , comprising:
one or more instructions for selecting at least one identified second treatment targeting at least one predicted pathogenic variant.