Methods and systems for treating disease
Methods and systems described herein are applicable to the identification of pathogens, pathogenic variants and applicable treatments or remedies. In some embodiments, the pathogen or pathogens bears a causal relationship to a disease state.
1 . A computer-implemented method comprising:
identifying a primary pathogen;
identifying a primary treatment targeting the primary pathogen;
predicting a first pathogenic variant of the primary pathogen;
identifying a set of first variant treatments targeting the first pathogenic variant;
predicting a second pathogenic variant of the primary pathogen; and
identifying a set of second variant treatments targeting the second pathogenic variant.
2 . The method as in claim 1 , comprising:
selecting at least one identified first variant treatment; and
selecting at least one identified second variant treatment.
3 . The method as in claim 2 , comprising:
administering the selected first variant treatment and the selected second variant treatment.
4 . The method as in claim 2 , comprising:
treating a disease state using a combination of treatments, including at least one selected first treatment and at least one selected second treatment.
5 . The method as in claim 3 , wherein the treatments are administered at the same time.
6 . The method as in claim 3 , wherein the treatments are administered at different times.
7 . The method as in claim 4 , wherein the treatments have the same route of delivery into the body of the individual being treated.
8 . The method as in claim 4 , wherein at least one of the selected treatments may be administered orally, via injection, via intravenous administration, transdermally, nasally, through the lung tissue or via inhalation.
9 . The method as in claim 4 , wherein at least one of the treatments is administered at a single time.
10 . The method as in claim 4 wherein at least one of the treatments comprises a series of treatments carried out over time.
11 . The method as in claim 1 , wherein the primary pathogen is a virus, a bacterium, a yeast, a mold, a fungus, a mycoplasma, a ureaplasma , a chlamydia , a rickettsia , a nanobacterium , a prion, an agent responsible for a transmissible spongiform encephalopathy (TSE), a multicellular parasite, a protein, an infectious protein, a nucleic acid, a metabolic by-product, a cellular by-product, or a toxin.
12 . The method as in claim 1 wherein the primary pathogen is associated with a disease state.
13 . The method as in claim 12 wherein the disease state affects a domestic animal.
14 . The method as in claim 12 wherein the disease state affects a human.
15 . The method as in claim 12 wherein the disease state affects a non-domesticated animal.
16 . The method as in claim 1 wherein at least one pathogenic variant is a virus, a bacterium, a yeast, a mold, a fungus, a mycoplasma, a ureaplasma , a chlamydia , a rickettsia , a nanobacterium , a prion, an agent responsible for a transmissible spongiform encephalopathy (TSE), a multicellular parasite, a protein, an infectious protein, a nucleic acid, a metabolic by-product, a cellular by-product, or a toxin.
17 . The method as in claim 1 wherein at least one predicted pathogenic variant is a previously identified variant.
18 . The method as in claim 1 wherein predicting at least one pathogenic variant is in response to a molecular model of the primary pathogen.
19 . The method as in claim 1 wherein predicting at least one first pathogenic variant includes accessing information from a database.
20 . The method as in claim 2 wherein selecting at least one treatment includes accessing information from a database.
21 . The method as in claim 2 wherein selecting at least one treatment is made in response to a molecular model of a primary pathogen and/or a pathogenic variant.
22 - 77 . (canceled)