Apparatus and methods for measuring pressure and flow in cardiac assist devices and peripheral vasculature
Disclosed are apparatus and methods for measuring pressure and/or flow in blood circulatory systems of a patient using cardiac assist devices. By way of example, a left ventricular assist device may be coupled between the left ventricle of the patient's heart and the aorta. One or more sensors, such as pressure sensors, are located at one or more selected locations in the heart, in blood-carrying conduits that are coupled to the cardiac assist device, or in the aorta, that sense pressure, for example, to monitor a patient's cardiac function. A monitoring device is coupled to the sensors that implements an algorithm that determines pressure and/or blood flow rate in the circulatory system using pressures and/or flow data derived from the sensors.
1 . Apparatus comprising:
a cardiac assist device coupled via blood-carrying conduits between a selected chamber of a patient's heart and a selected portion of the patient's blood circulatory system;
one or more sensors disposed in one or more of the blood-carrying conduits and/or a selected location in the patient's blood circulatory system that sense pressure and/or flow in the conduits and/or blood circulatory system; and
a monitoring device coupled to the one or more sensors for determining pressure and/or blood flow in the blood circulatory system using pressures and/or flow rates derived from the one or more sensors.
2 . The apparatus recited in claim 1 wherein the cardiac assist device comprises a left ventricular assist device that is coupled between the left ventricle of the patient's heart and the aorta.
3 . The apparatus recited in claim 1 wherein the cardiac assist device comprises a right ventricular assist device that is coupled between the right ventricle of the patient's heart and the pulmonary artery.
4 . The apparatus recited in claim 1 wherein the one or more sensors comprise pressure sensors.
5 . The apparatus recited in claim 1 wherein the cardiac assist device comprises a rotary ventricular assist device.
6 . The apparatus recited in claim 1 wherein the cardiac assist device comprises a multi-chamber assist device.
7 . The apparatus recited in claim 1 wherein the cardiac assist device comprises an atrial assist device.
8 . The apparatus recited in claim 1 wherein the one or more sensors are selectively disposed inside an inflow conduit of the cardiac assist device, at a second location in the inflow conduit, inside an outflow conduit of the cardiac assist device, at a second location in the outflow conduit, at a location within the aorta and external to the outflow conduit, at a second location within the aorta, or within a chamber of the heart adjacent to an input end of the inflow conduit.
9 . Apparatus comprising:
a left ventricular assist device coupled via blood-carrying conduits between the left ventricle of a patient's heart and the aorta;
one or more pressure sensors disposed in one or more of the blood-carrying conduits and/or the aorta that sense pressure and/or flow in the patient's blood circulatory system; and
a monitoring device coupled to the one or more sensors for determining pressure and/or blood flow in the blood circulatory system using pressures and/or flow rates derived from the one or more sensors.
10 . A method comprising:
coupling a cardiac assist device coupled via blood-carrying conduits between a selected chamber of a patient's heart and a selected portion of the patient's blood circulatory system;
disposing one or more sensors in one or more of the blood-carrying conduits and/or a selected location in the patient's blood circulatory system; and
determining pressure and/or flow in the patient's blood circulatory system using pressures and/or flow rates derived from the one or more sensors.
11 . The method recited in claim 10 wherein the cardiac assist device comprises a left ventricular assist device that is coupled between the left ventricle of the patient's heart and the aorta.
12 . The method recited in claim 10 wherein the cardiac assist device comprises a right ventricular assist device that is coupled between the right ventricle of the patient's heart and the pulmonary artery.
13 . The method recited in claim 10 wherein the one or more sensors are selectively disposed inside an inflow conduit of the cardiac assist device, at a second location in the inflow conduit, inside an outflow conduit of the cardiac assist device, at a second location in the outflow conduit, at a location within the aorta and external to the outflow conduit, at a second location within the aorta, or within a chamber of the heart adjacent to an input end of the inflow conduit.