Compositions containing lignan-class compounds
View Patent ↗An object of the invention is to provide compositions containing lignan-class compounds as dissolved at high concentrations. The compositions having lignan-class compounds such as sesamin and episesamin dissolved in solvent oils or fats that contain triglycerides of middle-chain fatty acids having 8-12 carbon atoms, preferably triglycerides of caprylic acid and/or capric acid and/or lauric acid can contain the lignan-class compounds stably at higher concentrations than when other solvents are used and, hence, have high enough value as foods and pharmaceuticals.
1. A composition consisting of:
a) sesamin and/or episesamin;
b) an oil or fat that contains a triglyceride of a middle-chain fatty acid having 8-12 carbon atoms, wherein a weight ratio of a total amount of sesamin and episesamin to a total amount of the triglyceride is about 1:40 to about 1:14.3; and
c) a vitamin, wherein the vitamin is selected from the group consisting of Vitamin E and Vitamin C,
wherein the composition has sesamin and/or episesamin dissolved therein.
2. The composition of claim 1 , wherein the vitamin is Vitamin E.
3. The composition of claim 1 , wherein the triglyceride of a middle-chain fatty acid comprises at least one middle-chain fatty acid selected from the group consisting of caprylic acid, capric acid, and lauric acid.
4. The composition of claim 1 , wherein the triglyceride of a middle-chain fatty acid comprises at least one triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
5. The composition of claim 1 , wherein the triglyceride of a middle-chain fatty acid consists of a triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
6. The composition of claim 5 , wherein all of the fatty acids constituting the MCT are selected from the group consisting of caprylic acid, capric acid, and lauric acid.
7. A composition consisting of:
a) at least 1.0 wt % episesamin;
b) an oil or fat that contains a triglyceride of a middle-chain fatty acid having 8-12 carbon atoms, wherein a weight ratio of an amount of episesamin to a total amount of the triglyceride is about 1:50 to about 1:40; and
c) a vitamin, wherein the vitamin is selected from the group consisting of Vitamin E and Vitamin C,
wherein the composition has episesamin dissolved therein.
8. The composition of claim 7 , wherein the vitamin is Vitamin E.
9. The composition of claim 7 , wherein the triglyceride of a middle-chain fatty acid comprises at least one middle-chain fatty acid selected from the group consisting of caprylic acid, capric acid, and lauric acid.
10. The composition of claim 7 , wherein the triglyceride of a middle-chain fatty acid comprises at least one triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
11. The composition of claim 7 , wherein the triglyceride of a middle-chain fatty acid consists of a triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
12. The composition of claim 11 , wherein ail of the fatty acids constituting the MCT are selected from the group consisting of caprylic acid, capric acid, and lauric acid.
13. A composition consisting of:
sesamin and/or episesamin;
b) an oil or fat that contains a triglyceride of a middle-chain fatty acid having 8-12 carbon atoms, wherein the triglyceride of a middle-chain fatty acid comprises at least one triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT), and wherein a total amount of the MCT(s) is 25-100% by weight of a total amount of the oil or fat; and
c) a vitamin, wherein the vitamin is selected from the group consisting of Vitamin E and Vitamin C,
wherein the composition has sesamin and/or episesamin dissolved therein.
14. The composition of claim 13 , wherein the vitamin is Vitamin E.
15. The composition of claim 13 , wherein the triglyceride of a middle-chain fatty acid consists of a triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
16. The composition of claim 15 , wherein all of the fatty acids constituting the MCT are selected from the group consisting of caprylic acid, capric acid, and lauric acid.
17. A composition consisting of:
a) sesamin and/or episesamin;
b) an oil or fat that contains a triglyceride of a middle-chain fatty acid having 8-12 carbon atoms, wherein a weight ratio of a total amount of sesamin and episesamin to a total amount of the triglyceride is about 1:40 to about 1:14.3;
c) a vitamin, wherein the vitamin is selected from the group consisting of Vitamin E and Vitamin C; and
d) an additive selected from the group consisting of a sugar, a vehicle, a disintegrant, a binder, a lubricant, an emulsifier, an isotonization agent, a buffer, a solvent promoter, a preservative, a stabilizer, an antioxidant, a coloring agent, a flavoring agent, a scent, a coagulant, a pH adjuster, a thickening agent, an extract powder, a galenical, and an inorganic salt,
wherein the composition has sesamin and/or episesamin dissolved therein.
18. The composition of claim 17 , wherein the vitamin is Vitamin E.
19. The composition of claim 17 , wherein the triglyceride of a middle-chain fatty acid comprises at least one middle-chain fatty acid selected from the group consisting of caprylic acid, capric acid, and lauric acid.
20. The composition of claim 17 , wherein the triglyceride of a middle-chain fatty acid comprises at least one triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
21. The composition of claim 17 , wherein the triglyceride of a middle-chain fatty acid consists of a triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
22. The composition of claim 21 , wherein all of the fatty acids constituting the MCT are selected from the group consisting of caprylic acid, capric acid, and lauric acid.
23. A composition consisting of:
a) at least 1.0 wt % episesamin;
b) an oil or fat that contains a triglyceride of a middle-chain fatty acid having 8-12 carbon atoms, wherein a weight ratio of an amount of episesamin to a total amount of the triglyceride is about 1:50 to about 1:40;
c) a vitamin, wherein the vitamin is selected from the group consisting of Vitamin E and Vitamin C; and
d) an additive selected from the group consisting of a sugar, a vehicle, a disintegrant, a binder, a lubricant, an emulsifier, an isotonization agent, a buffer, a solvent promoter, a preservative, a stabilizer, an antioxidant, a coloring agent, a flavoring agent, a scent, a coagulant, a pH adjuster, a thickening agent, an extract powder, a galenical, and an inorganic salt,
wherein the composition has episesamin dissolved therein.
24. The composition of claim 23 , wherein the vitamin is Vitamin E.
25. The composition of claim 23 , wherein the triglyceride of a middle chain fatty acid comprises at least one middle-chain fatty acid selected from the group consisting of caprylic acid, capric acid, and lauric acid.
26. The composition of claim 23 , wherein the triglyceride of a middle-chain fatty acid comprises at least one triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
27. The composition of claim 23 , wherein the triglyceride of a middle-chain fatty acid consists of a triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
28. The composition of claim 27 , wherein all of the fatty acids constituting the MCT are selected from the group consisting of caprylic acid, capric acid, and lauric acid.
29. A composition consisting of;
a) sesamin and/or episesamin;
b) an oil or fat that contains a triglyceride of a middle-chain fatty acid having 8-12 carbon atoms, wherein the triglyceride of a middle-chain fatty acid comprises at least one triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT), and wherein a total amount of the MCT(s) is 25100% by weight of a total amount of the oil or fat;
c) a vitamin, wherein the vitamin is selected from the group consisting of Vitamin E and Vitamin C; and
d) an additive selected from the group consisting of a sugar, a vehicle, a disintegrant, a binder, a lubricant, an emulsifier, an isotonization agent, a buffer, a solvent promoter, a preservative, a stabilizer, an antioxidant, a coloring agent, a flavoring agent, a scent, a coagulant, a pH adjuster, a thickening agent, an extract powder, a galenical, and an inorganic salt,
wherein the composition has sesamin and/or episesamin dissolved therein.
30. The composition of claim 29 , wherein the vitamin is Vitamin E.
31. The composition of claim 29 , wherein the triglyceride of a middle-chain fatty acid consists of a triglyceride in which all constituent fatty acids are middle-chain fatty acids (MCT).
32. The composition of claim 31 , wherein all of the fatty acids constituting the MCT are selected from the group consisting of caprylic acid, capric acid, and lauric acid.