IP Library Granted Patent US 8,469,331
Granted Patent B2
US 8,469,331 · App. 12/296,415 · Granted Jun 25, 2013

Filtration system for preparation of fluids for medical applications

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Quick Facts
Patent No.
US 8,469,331
App. No.
12/296,415
Granted
Jun 25, 2013
Kind
B2
Abstract

Systems, methods, and devices for preparation of purified water and medicaments for various uses including blood treatment are described. Methods, devices, and systems for creating multiple-treatment batches are described.

Claims (22)

1. A fluid line sealing device comprising:

a tube connected to a port of a batch fluid container, the tube being configured to transport fluid through an interior thereof;

a clamping member arranged on an exterior of the tube such that the clamping member can be moved along the tube, the clamping member being configured to hold a portion of the tube in a folded configuration so as to prevent fluid from flowing through said interior; and

a sliding collar arranged on an exterior of the tube such that the sliding collar can be moved along the tube and held in place on the tube by friction and having a substantially cylindrical shape, the sliding collar being configured to interact with said portion of the tube such that patency of said portion of the tube is restored in an unfolded configuration after said folded configuration,

wherein an inner diameter of the sliding collar is substantially the same as an outer diameter of the tube.

2. The fluid line sealing device of claim 1 , wherein the clamping member has a clamping portion and a leash portion, the clamping portion holds the portion of the tube in the folded configuration, the tube is completely external to an interior of the clamping portion in the unfolded configuration, and the leash portion supports the clamping member on the tube in both the folded and unfolded configurations.

3. The fluid line sealing device of claim 1 , wherein the clamping member includes a retaining portion for supporting the clamping member on the tube when the tube is in the unfolded configuration.

4. The fluid line sealing device of claim 1 , wherein the sliding collar and the clamping member are configured such that the clamping member does not obstruct motion of the sliding collar when the tube is in the unfolded configuration.

5. The fluid line sealing device of claim 1 , wherein the sliding collar is arranged on the exterior of the tube separately from the clamping member.

6. The fluid line sealing device of claim 1 , wherein the sliding collar is elongate and has a constant cross section.

7. The fluid line sealing device of claim 1 , wherein the sliding collar is closely conforming over length of the tube to allow for restoration of patency of said portion of the tube.

8. A method of controlling flow in a fluid line, comprising:

holding the tubing in a bent configuration so as to form the folded portion which seals the tubing;

after the holding, straightening a folded portion of tubing to unseal it; and

placing a restoring member over the straightened folded portion of the tubing to increase patency of a lumen of the tubing,

wherein the holding includes providing a removable holding member which maintains the tubing in a folded state.

9. The method of claim 8 , wherein the straightening includes moving the holding member that holds the tubing in the folded state.

10. The method of claim 9 , wherein the holding member defines a substantially cylindrical portion which surrounds portions of the tubing on either side of the folded portion.

11. The method of claim 10 , wherein the holding member remains movably attached to the tubing after the straightening.

12. The method of claim 8 , wherein the restoring member is a tubular element with an internal diameter substantially equal to an outer diameter of the tubing, the tubular element being configured to surround the tubing on either side of the straightened folded portion.

13. The method of claim 12 , wherein the restoring member is closely conforming over a length of the tubing to allow for increasing patency of the lumen.

14. The method of claim 8 , further comprising, flowing fluid through said tubing to or from a batch container connected thereto.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Feb 21, 2019
From: CAPITAL ONE, NATIONAL ASSOCIATION (AS SUCCESSOR BY MERGER TO HEALTHCARE FINANCIAL SOLUTIONS, LLC)
To: NXSTAGE MEDICAL, INC.
Reel/Frame 048407/0865 →
ASSIGNMENT OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 16, 2015
From: GENERAL ELECTRIC CAPITAL CORPORATION, AS RETIRING AGENT
To: HEALTHCARE FINANCIAL SOLUTIONS, LLC, AS SUCCESSOR AGENT
Reel/Frame 037112/0376 →
RELEASE OF SECURITY INTEREST Recorded Jun 11, 2014
From: SILICON VALLEY BANK
To: NXSTAGE MEDICAL, INC.
Reel/Frame 033133/0902 →
SECURITY INTEREST Recorded Jun 10, 2014
From: NXSTAGE MEDICAL, INC.
To: GENERAL ELECTRIC CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT
Reel/Frame 033123/0836 →
SECURITY AGREEMENT Recorded Mar 22, 2010
From: NXSTAGE MEDICAL, INC.
To: SILICON VALLEY BANK
Reel/Frame 024114/0789 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2008
From: BURBANK, JEFFREY H.; TREU, DENNIS M.; FREIDERICHS, GOETZ; BURGGER, JAMES M.; GREEN, BRIAN C.; MCDOWELL, CHRISTOPHER S.
To: NXSTAGE MEDICAL, INC.
Reel/Frame 021746/0475 →