The present invention relates to scaffolds which can be used as medical devices for guided tissue regeneration and repair, in particular the invention is directed to a scaffold comprising fibers having a mean fiber diameter of between from about 1.2 to 4.0 microns, wherein the fibers comprise a glycolide. The invention further relates to the use of the scaffolds for the selective capture of cell populations for a cell source material.
1. A scaffold comprising fibres having a mean fibre diameter of between 1.9 to 2.6 microns, and wherein said fibres comprise over 95% glycolide.
2. A scaffold according to claim 1 , wherein the fibre comprises over 90% polymer.
3. A scaffold according to claim 2 , wherein the fibre comprises over 95% polymer.
4. A scaffold according to claim 2 , wherein the fibre consists of 100% polymer.
5. A scaffold according to claim 2 , wherein the polymer consists of 100% glycolide.
6. A scaffold according to claim 1 , wherein the glycolide is polyglycolic acid.
7. A scaffold according to claim 1 , wherein the fibre comprises a copolymer of a glycolide and a hydroxy acid.
8. A scaffold according to claim 7 , wherein the hydroxy acid is a lactide.
9. A scaffold according to claim 8 , wherein the co-polymer is poly(lactide-co-glycolide).
10. A scaffold according to claim 1 , wherein the scaffold is a non-woven.
11. A scaffold according to claim 1 , wherein the fibres are electrospun.
12. A medical dressing comprising a scaffold comprising fibres having a mean fibre diameter of between 1.9 to 2.6 microns, and wherein said fibres comprise over 95% glycolide.
13. A medical dressing according to claim 12 , wherein the dressing is a wound dressing.
14. A medical dressing according to claim 12 , wherein the fibre comprises over 90% polymer.
15. A medical dressing according to claim 12 , wherein the glycolide is polyglycolic acid.
16. A medical dressing according to claim 12 , wherein the fibre comprises a copolymer of a glycolide and a hydroxy acid.
17. A medical dressing according to claim 16 , wherein the hydroxy acid is a lactide.
18. A medical dressing according to claim 17 , wherein the co-polymer is poly(lactide-co-glycolide).
19. A medical dressing according to claim 12 , wherein the scaffold is a non-woven.
20. A medical dressing according to claim 12 , wherein the fibres are electrospun.