IP Library Granted Patent US 8,318,927
Granted Patent B2
US 8,318,927 · App. 12/301,919 · Granted Nov 27, 2012

6-(4-cyclopropylpiperazin-1-yl)-2′-methyl-[3, 4′]-bipyridine and its uses as a medicament

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Quick Facts
Patent No.
US 8,318,927
App. No.
12/301,919
Granted
Nov 27, 2012
Kind
B2
Abstract

6-(4-Cyclopropylpiperazin-1-yl)-2′-methyl-[3,4′]bipyridinyl and salts and hydrates thereof interact with the histamine H3 receptor are defined.

Claims (12)

1. A compound of Formula (I)

or a pharmaceutically acceptable salt thereof.

2. The compound of claim 1 , where the compound is in the form of a hydrochloride salt.

3. The compound of claim 2 , where the compound is in the form of a trihydrochloride salt.

4. The compound of claim 1 , where the compound is in the form of a trifluoroacetate salt.

5. The compound of claim 4 , where the compound is in the form of a mono-trifluoroacetate salt.

6. A pharmaceutical composition comprising: a compound of Formula (I)

or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier or diluent.

7. The pharmaceutical composition of claim 6 , where the compound is in the form of a hydrochloride salt.

8. The pharmaceutical composition of claim 7 , where the compound is in the form of a trihydrochloride salt.

9. The pharmaceutical composition of claim 6 , where the compound is in the form of a trifluoroacetate salt.

10. The pharmaceutical composition of claim 9 , where the compound is in the form of a mono-trifluoroacetate salt.

Assignments (8)
CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY DATA PREVIOUSLY RECORDED AT REEL: 036254 FRAME: 0792. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Sep 24, 2015
From: M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT
To: VTVX HOLDINGS II LLC
Reel/Frame 036675/0399 →
RELEASE OF SECURITY INTEREST Recorded Aug 3, 2015
From: M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT
To: VTVX HOLDINGS I LLC
Reel/Frame 036254/0792 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2015
From: VTVX HOLDINGS II LLC
To: VTV THERAPEUTICS LLC
Reel/Frame 036242/0362 →
CHANGE OF NAME Recorded Jul 30, 2015
From: HIGH POINT PHARMACEUTICALS, LLC
To: VTVX HOLDINGS II LLC
Reel/Frame 036236/0159 →
SECURITY INTEREST Recorded Feb 26, 2015
From: HIGH POINT PHARMACEUTICALS, LLC
To: M&F TTP HOLDINGS LLC, AS COLLATERAL AGENT
Reel/Frame 035103/0029 →
NOTICE OF RELEASE OF SECURITY INTEREST IN PATENTS FOR REEL/FRAME 030982/0793 Recorded Apr 7, 2014
From: M&F TTP HOLDINGS LLC
To: HIGH POINT PHARMACEUTICALS, LLC
Reel/Frame 032621/0867 →
SECURITY AGREEMENT Recorded Aug 9, 2013
From: HIGH POINT PHARMACEUTICALS, LLC
To: M&F TTP HOLDINGS LLC C/O MACANDREWS & FORBES HOLDINGS INC.
Reel/Frame 030982/0793 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2009
From: LUNDBECK, JANE MARIE; HOHLWEG, ROLF
To: HIGH POINT PHARMACEUTICALS, LLC
Reel/Frame 022126/0134 →