IMPLANTABLE MEDICAL DEVICES COMPRISING CATHODIC ARC PRODUCED STRUCTURES
Implantable medical devices that include cathodic arc produced structures are provided. Cathodic arc produced structures of the invention may be thick, stress-free metallic structures that have configurations heretofore not available in implantable medical devices. In yet other embodiments, the structures may be crenulated or porous layers. Also provided are methods of producing implantable medical devices as well as systems for practicing the subject methods.
1 . An implantable medical device comprising a cathodic arc produced structure.
2 . The implant according to claim 1 , wherein said cathodic arc produced structure is a stress-free structure having a thickness ranging from about 1 μm to about 100 μm.
3 . The implant according to claim 2 , wherein said structure is a layer that covers at least a portion of surface a component of said implant.
4 . The implant according to claim 3 , wherein said layer seals an internal volume of said implant.
5 . The implant according to claim 2 , wherein said structure is a component of said implant.
6 . The implant according to claim 5 , wherein said component is a conductive element.
7 . The implant according to claim 6 , wherein said conductive element is present in a high aspect ratio passage of said implant.
8 . The implant according to claim 5 , wherein said component is an effector.
9 . The implant according to claim 8 , wherein said effector is an actuator.
10 . The implant according to claim 8 ; wherein said effector is a sensor.
11 . The implant according to claim 1 , wherein said cathodic arc produced structure is a microstrip antenna.
12 . The medical device according to claim 11 , wherein said microstrip antenna comprises a cathodic arc produced radiator patch layer on a surface of a substrate layer.
13 . The implant according to claim 1 , wherein said cathodic arc produced structure is a crenulated layer.
14 . The implant according to claim 13 , wherein said crenulated layer is present on an implant.
15 . The implant according to claim 14 , wherein said crenulated layer further comprises a pharmaceutically active agent.
16 . The implant according to claim 1 , wherein said cathodic arc produced structure is a porous layer.
17 . The implant according to claim 16 , wherein said porous layer is part of a high surface area electrode.
18 . A method of producing a metallic structure on a substrate, said method comprising:
contacting a cathodic arc generated metallic ion plasma with a surface of said substrate to produce a deposited metallic stress-free structure having a thickness of about 1 μm or greater on said substrate.
19 . The method according to claim 18 , wherein said contacting occurs in a manner such that compressive and tensile forces experienced by said deposited metal structure substantially cancel each other out so that said deposited metal structure is stress-free.
20 . The method according to claim 18 , wherein plasma is contacted with said surface in a direction that is substantially orthogonal to a plane of said surface.
21 . The method according to claim 18 , wherein said method is a method of producing a portion of an implantable medical device.
22 . The method according to claim 21 , wherein said portion is a component of said implantable medical device.
23 . The method according to claim 22 , wherein said component is a conductive element.
24 . The method according to claim 23 , wherein said conductive element is present in a high aspect ratio passage of said implant.
25 . The method according to claim 24 , wherein said high aspect ratio structure has a height to width ratio ranging from about 1 to about 50.
26 . The method according to claim 21 , wherein said portion is a metallic layer that covers at least a portion of said surface.
27 . The method according to claim 26 , wherein said metallic layer seals an internal space of said substrate.
28 . The method according to claim 18 , wherein said metallic structure comprises a physiologically compatible metal.
29 . The method according to claim 28 , wherein said metal is chosen from platinum, iridium and titanium.
30 . The method according to claim 18 , wherein said plasma is generated in a vacuum.
31 . The method according to claim 18 , wherein said plasma is generated in the presence of oxygen.
32 . The method according to claim 18 , wherein said plasma is generated in the presence of nitrogen.
33 . The method according to claim 18 , wherein said plasma is generated in the presence of carbon.
34 . A cathodic arc plasma deposition system comprising:
a cathodic arc plasma source; and
a substrate mount, wherein said substrate mount includes a temperature modulator for modulating the temperature of a substrate mounted thereon.
35 . The cathodic arc plasma deposition system according to claim 34 , wherein the distance between said substrate mount and said cathodic arc plasma source may be adjusted.
36 . The cathodic arc plasma deposition system according to claim 35 , wherein said system includes a plasma filter.
37 . The cathodic arc plasma deposition system according to claim 35 , wherein said system includes a plasma beam biasing element.