Small molecule inhibitors of BCL6
View Patent ↗Provided are methods of inhibiting BCL6 repression in a mammalian cell. Also provided are methods of treating cancer in a mammal.
1. A compound having the structure:
or a pharmaceutically acceptable salt thereof.
2. A composition for inhibiting BCL6 comprising the compound of claim 1 .
3. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable carrier.
4. The pharmaceutical composition of claim 3 , formulated for parenteral administration.
5. A compound having the structure:
or a pharmaceutically acceptable salt thereof.
6. A composition for inhibiting BCL6 comprising the compound of claim 5 .
7. A pharmaceutical composition comprising the compound of claim 5 and a pharmaceutically acceptable carrier.
8. The pharmaceutical composition of claim 7 , formulated for parenteral administration.
9. A compound having the structure:
or a pharmaceutically acceptable salt thereof.
10. A composition for inhibiting BCL6 comprising the compound of claim 9 .
11. A pharmaceutical composition comprising the compound of claim 9 and a pharmaceutically acceptable carrier.
12. The pharmaceutical composition of claim 11 , formulated for parenteral administration.