Resorbable nanoenhanced hemostatic structures and bandage materials
View Patent ↗Methods, systems, and apparatuses for nanomaterial-enhanced hemostatic medical devices are provided. Hemostatic materials and structures are provided that induce coagulation of blood at a wound/opening caused by trauma, a surgical procedure, ulceration, or other cause. The hemostatic materials and structures may incorporate nanostructures and/or further hemostatic elements such as polymers and/or glass beads. The hemostatic materials and structures may be resorbable. Example embodiments include hemostatic bandages, hemostatic plugs, and hemostatic formulations.
1. A hemostatic structure, comprising:
a base structure that includes a first material; and
a plurality of nanostructures incorporated with the base structure, wherein the nanostructures include at least one of nanofibers or nanorods;
wherein the nanostructures comprise at least one semiconductor material and are configured to induce hemostasis when the hemostatic structure is contacted with blood.
2. The hemostatic structure of claim 1 , wherein the base structure includes a woven or nonwoven fiber of the first material.
3. The hemostatic structure of claim 2 , wherein the first material is a natural fiber.
4. The hemostatic structure of claim 2 , wherein the first material is a synthetic fiber.
5. The hemostatic structure of claim 2 , wherein the fiber is a glass microfiber.
6. The hemostatic structure of claim 1 , wherein the nanostructures include silicon nanowires.
7. The hemostatic structure of claim 6 , wherein the silicon nanowires have a thin naturally occurring oxide shell layer.
8. The hemostatic structure of claim 1 , wherein the nanostructures coat the base structure.
9. The hemostatic structure of claim 1 , wherein the first material is resorbable.
10. The hemostatic structure of claim 1 , wherein the first material includes cotton.
11. The hemostatic structure of claim 1 , wherein the first material includes oxidized cellulose.
12. The hemostatic structure of claim 1 , wherein the first material includes collagen.
13. The hemostatic structure of claim 1 , wherein the first material includes a biologically-derived material.
14. The hemostatic structure of claim 1 , wherein the first material is an organic or inorganic polymer.
15. The hemostatic structure of claim 1 , wherein the hemostatic structure is a bandage.
16. The hemostatic structure of claim 1 , wherein the base structure is a bandage.
17. A hemostat, comprising:
a material; and
a plurality of nanostructures comprising at least one semiconductor material, wherein the nanostructures include at least one of nanofibers, nanorods, or nanotubes;
wherein the material and the nanostructures form a mixture.
18. The hemostat of claim 17 , wherein the nanostructures include nanofibers.
19. The hemostat of claim 18 , wherein the nanofibers are coated with silicon dioxide.
20. The hemostat of claim 18 , wherein the nanofibers are potassium nanofibers.
21. The hemostat of claim 18 , wherein the nanofibers are silicon nanofibers functionalized with potassium.
22. The hemostat of claim 17 , wherein the material comprises chitosan.
23. The hemostat of claim 22 , wherein the material comprises chitosan microparticles.
24. The hemostat of claim 17 , wherein the material comprises biocompatible polymers.
25. A method for forming a hemostatic structure, comprising:
incorporating nanostructures with a first material to form the hemostatic structure.
26. The method of claim 25 , wherein said incorporating comprises:
incorporating the nanostructures with a weave of fibers of the first material to form the hemostatic structure; and
coating the weave of fibers with the nanostructures to form the hemostatic structure; and wherein said coating comprises:
sonicating a wafer coated with nanostructures in a liquid;
filtering the sonicated nanostructures;
suspending the filtered nanostructures in a liquid to form a nanostructure suspension;
soaking the weave of fibers in the nanostructure suspension; and
drying the soaked weave of fibers.