IP Library Granted Patent US 8,163,739
Granted Patent B2
US 8,163,739 · App. 12/331,775 · Granted Apr 24, 2012

2-arylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals

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Quick Facts
Patent No.
US 8,163,739
App. No.
12/331,775
Granted
Apr 24, 2012
Kind
B2
Abstract

The present invention relates to 2-arylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof

Claims (12)

1. 2-(3-Methanesulphonylphenyl)-thiazole-4-(3-carbamoyl-1-methyl-1H-pyrazol-4-yl)-carboxamide

N-[5-(Aminocarbonyl)-1-methyl-1H-pyrazol-4-yl]-2-(2,3-dihydro-5-benzofuranyl)-4-thiazolecarboxamide

N-[2-(Aminocarbonyl)-4-methylphenyl]-2-(2,3-dihydro-5-benzofuranyl)-4-thiazolecarboxamide

N-[2-(Aminocarbonyl)-4-chlorophenyl]-2-(2,3-dihydro-5-benzofuranyl)-4-thiazolecarboxamide

N-[2-(Aminocarbonyl)phenyl]-2-(2,3-dihydro-5-benzofuranyl)-4-thiazolecarboxamide

2-{[2-(2,3-Dihydrobenzofuran-5-yl)-thiazole-4-carbonyl]-amino}-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide

N-[2-(Aminocarbonyl)phenyl]-2-(3,4-methylenedioxyphenyl)-4-thiazolecarboxamide

N-[2-(Aminocarbonyl)phenyl]-2-(3-methylsulphonylphenyl)-4-thiazolecarboxamide

N-[2-(Aminocarbonyl)phenyl]-2-(3-cyanophenyl)-4-thiazolecarboxamide

N-[2-(Aminocarbonyl)phenyl]-2-(3-fluoro-4-methoxyphenyl)-4-thiazolecarboxamide or

N-[2-(Aminocarbonyl)-5-methylphenyl]-2-(4-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-thiazole-4-carboxamide.

2. A pharmaceutical composition comprising a compound according to claim 1 , and a pharmaceutically acceptable carrier.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 30, 2013
From: BAYER PHARMA AKTIENGESELLSCHAFT
To: BAYER INTELLECTUAL PROPERTY GMBH
Reel/Frame 030516/0512 →
CHANGE OF NAME Recorded Dec 2, 2011
From: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
To: BAYER PHARMA AKTIENGESELLSCHAFT
Reel/Frame 027318/0877 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 2, 2009
From: BOTHE, ULRICH; VON BONIN, ARNE; NGUYEN, DUY; BOMER, ULF; GUENTHER, JUDITH
To: BAYER SCHERING PHARMA AG
Reel/Frame 022330/0345 →