IP Library Granted Patent US 7,866,209
Granted Patent B2
US 7,866,209 · App. 12/333,814 · Granted Jan 11, 2011

Fluid level regulator

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,866,209
App. No.
12/333,814
Granted
Jan 11, 2011
Kind
B2
Abstract

A biological specimen collection and transfer system, including a biological sample container configured for storing a biological fluid sample, a vacuum source, a specimen filter having an interior chamber and an opening in communication with the chamber, and a fluid level regulator configured to determine a fluid level in the biological sample container and to dispense a fluid into the container if the determined fluid level is less than a desired fluid level. The fluid level regulator includes a fluid level monitor, a fluid dispenser, and a controller in communication with the fluid level monitor and the fluid dispenser, wherein the fluid level monitor includes a sound source configured to emit sound towards a surface of the fluid sample, and a sound detector configured to measure sound reflected from the surface of the fluid sample, wherein the controller determines the fluid level based at least in part on a measurement of reflected sound emitted from the sound source.

Claims (31)

1. A biological specimen collection and transfer system, comprising:

a biological sample container configured for storing a biological fluid sample;

a vacuum source;

a specimen filter having an interior chamber and an opening in communication with the chamber; and

a fluid level regulator configured to determine a fluid level in the biological sample container and to dispense a fluid into the container if the determined fluid level is less than a desired fluid level, wherein the fluid level regulator comprises:

a fluid level monitor;

a fluid dispenser; and

a controller in communication with the fluid level monitor and the fluid dispenser,

wherein the fluid level monitor comprises

a sound source configured to emit sound towards a surface of the fluid sample, and

a sound detector configured to measure sound reflected from the surface of the fluid sample, wherein the controller determines the fluid level based at least in part on a measurement of reflected sound emitted from the sound source.

2. The system of claim 1 , further comprising a filtration based biological specimen slide processor.

3. The system of claim 1 , further comprising

a vacuum conduit configured to couple the vacuum source to the specimen filter chamber.

4. The system of claim 1 , further comprising an elevator for moving the sample container relative to the specimen filter, wherein the controller uses a relative position of the elevator in determining the fluid level.

5. The system of claim 1 , wherein the opening in the specimen filter is positioned at the desired fluid level.

6. A biological specimen collection and transfer system, comprising:

a biological sample container configured for storing a biological fluid sample, the fluid sample container being translucent;

a fluid level regulator configured to determine a fluid level in the biological sample container and to dispense a fluid into the container if the determined fluid level is less than a desired fluid level, wherein the fluid level regulator comprises:

a fluid level monitor;

a fluid dispenser; and

a controller in communication with the fluid level monitor and the fluid dispenser,

wherein the fluid level monitor comprises

a sound source configured to emit sound towards a surface of the fluid sample, and

a sound detector configured to measure sound reflected from the surface of the fluid sample, wherein the controller determines the fluid level based at least in part on a measurement of reflected sound emitted from the sound source.

7. The system of claim 6 , further comprising a filtration based biological specimen slide processor.

8. A method of regulating a fluid level of a biological fluid sample in a container during a process of transferring biological matter in the fluid sample to a specimen slide, the method comprising:

monitoring a pressure of an interior chamber of a specimen filter, the chamber coupled to a vacuum source and having one end submerged in the fluid sample; and

monitoring a fluid level of the fluid sample in the container based on a measurement of sound emitted from a sound source and reflected from a surface of the fluid sample.

9. The method of claim 8 , further comprising adding a liquid to the container if the fluid level is less than a desired fluid level.

10. The method of claim 9 , wherein the fluid is added automatically upon a determination that the fluid level is less than a desired fluid level, until a further determination is made that the fluid level is at or above a desired fluid level.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 25, 2012
From: TENNEY, DOUGLAS A.
To: CYTYC CORPORATION
Reel/Frame 028636/0420 →