IP Library › Granted Patent US 8,030,456
Granted Patent B2
US 8,030,456 · App. 12/335,328 · Granted Oct 4, 2011

Nogo receptor antagonists

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Quick Facts
Patent No.
US 8,030,456
App. No.
12/335,328
Granted
Oct 4, 2011
Kind
B2
Abstract

Disclosed are immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are compositions comprising, and methods for making and using, such Nogo receptor antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same.

Claims (2)

1. A hybridoma cell line selected from the group consisting of: HB 7E11 (ATCC accession No. PTA-4587), HB 1H2 (ATCC accession No. PTA-4584), HB 3G5 (ATCC accession No. PTA-4586), HB 5B10 (ATCC accession No. PTA-4588) and HB 2F7 (ATCC accession No. PTA-4585).

2. An isolated antibody produced by the hybridoma cell line of claim 1 , or antigen-binding fragment thereof.

Assignments (4)
SECURITY INTEREST Recorded Apr 19, 2017
From: AXERION THERAPEUTICS, INC.
To: CONNECTICUT INNOVATIONS, INCORPORATED; SMITH, ERIKA R.
Reel/Frame 042052/0121 →
SECURITY INTEREST Recorded Jun 12, 2015
From: AXERION THERAPEUTICS, INC.
To: CONNECTICUT INNOVATIONS, INCORPORATED
Reel/Frame 035898/0809 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2011
From: STRITTMATTER, STEPHEN M.
To: YALE UNIVERSITY
Reel/Frame 026823/0304 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2011
From: LEE, DANIEL H.S.; PEPINSKY, R. BLAKE; LI, WEIWEI; RELTON, JANE K.; WORLEY, DANE S.; SAH, DINAH W.Y.; RABACCHI, SYLVIA A.
To: BIOGEN IDEC MA INC.
Reel/Frame 026823/0325 →