IP Library Granted Patent US 8,325,414
Granted Patent B2
US 8,325,414 · App. 12/335,440 · Granted Dec 4, 2012

Apparatus for single-handed control of microscope functions

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Quick Facts
Patent No.
US 8,325,414
App. No.
12/335,440
Granted
Dec 4, 2012
Kind
B2
Abstract

Apparatus for single-handed control of a microscope are disclosed. In one embodiment, a first controller, such as a first rotary controller, is configured for manipulation by a hand of a user to adjust a position of a microscope stage. Another controller, such as a second rotary controller, is configured and arranged relative to the first rotary controller for manipulation by an extended finger of the same hand to review, e.g., scroll through, previously identified portions of a biological specimen while the user's first hand may or may not remain in contact with the first rotary controller. In this manner, the user may continue to review the previously identified specimen portions without having to look away from the microscope.

Claims (30)

1. A review microscope, comprising:

an objective lens having a field of view;

a stage having a specimen slide disposed thereon;

a motor operatively coupled to the stage and configured to move the stage;

a processor operatively coupled to the motor and configured to control operation of the motor to thereby control movement of the stage;

coarse and fine focus controllers operatively coupled to the stage;

a control interface extending substantially horizontally from the stage;

a first rotary controller extending substantially vertically from the control interface and configured for manipulation by an extended finger of a single hand of an operator to cause the processor to automatically position the stage to present a previously identified object of interest on the specimen slide in the field of view of the objective lens; and

a second rotary controller extending substantially vertically from the control interface and configured for manipulation by hand to further adjust a position of the stage to adjust a position of the object of interest within the field of view,

wherein the first and second rotary controllers are arranged relative to each other to allow the extended finger to manipulate the first rotary controller, while the hand contacts the second rotary controller,

wherein the second rotary controller is a coaxial rotary controller comprising

a first rotary control element configured for moving the microscope stage in a first direction, and

a second rotary control element coaxial with the first rotary control element and configured for moving the microscope stage in a second direction different than the first direction.

2. The microscope of claim 1 , wherein the first rotary controller and the second rotary controller are rotatable about substantially parallel axes of rotation.

3. The microscope of claim 1 , wherein the second rotary controller element is configured for manipulation by a thumb of the single hand, and the first rotary control element is configured for manipulation by at least one finger of the hand.

4. The microscope of claim 3 , wherein the second rotary controller is configured for manipulation by an extended finger different from the at least one finger that is used for manipulation of the first rotary controller.

5. The microscope of claim 1 , wherein the second rotary controller is further configured for manipulation by an index finger of the operator's hand while the index finger is not extended.

6. The microscope of claim 1 , wherein the first rotary controller is a scroll wheel.

7. The microscope of claim 1 , further comprising

a switch associated with the first rotary controller and configured to be actuated as a result of displacement of the first rotary controller by the operator's extended finger to electronically mark a previously identified portion of the specimen slide.

8. The microscope of claim 7 , wherein the first rotary controller and the switch are configured such that the switch is actuated by lateral displacement of the first rotary controller.

9. The microscope of claim 7 , wherein the first rotary controller and the switch are configured such that the switch is actuated by vertical displacement of the first rotary controller.

10. The microscope of claim 1 , wherein the first rotary controller is a rotary encoder.

11. The microscope of claim 10 , wherein a position of the rotary encoder determines which previously identified portion of the specimen slide is presented to the operator.

12. A method of reviewing a specimen slide containing a plurality of previously identified objects of interest, the method comprising:

mounting the specimen slide on a stage of a review microscope;

rotating a first controller of the review microscope using an extended finger of a hand to cause a processor to automatically position the stage to present a previously identified object of interest on the specimen slide in a field of view of an objective lens of the microscope; and

rotating a second controller using the hand to further adjust a position of the stage to thereby adjust a position of the object of interest within the field of view, wherein the first and second rotary controllers are arranged relative to each other to allow the extended finger to manipulate the first rotary controller while the hand contacts the second rotary controller.

13. The method of claim 12 , further comprising displacing the first controller to electronically mark a previously identified portion of the specimen slide.

14. The microscope of claim 1 , wherein the first rotary controller and the second rotary controller have different axes of rotation.

Assignments (10)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
TERMINATION OF PATENT SECURITY AGREEMENTS AND RELEASE OF SECURITY INTERESTS Recorded Aug 26, 2010
From: GOLDMAN SACHS CREDIT PARTNERS, L.P., AS COLLATERAL AGENT
To: HOLOGIC, INC.; R2 TECHNOLOGY, INC.; SUROS SURGICAL SYSTEMS, INC.; BIOLUCENT, LLC; DIRECT RADIOGRAPHY CORP.; CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP; CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS III, INC.; CYTYC PRENATAL PRODUCTS CORP.; THIRD WAVE TECHNOLOGIES, INC.
Reel/Frame 024892/0001 →
SIXTH SUPPLEMENT TO PATENT SECURITY AGREEMENT Recorded Jan 27, 2009
From: CYTYC CORPORATION
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 022163/0844 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 15, 2008
From: GUINEY, PATRICK
To: CYTYC CORPORATION
Reel/Frame 021981/0794 →