IP Library Granted Patent US 7,731,711
Granted Patent B2
US 7,731,711 · App. 12/336,866 · Granted Jun 8, 2010

Cryosurgical instrument and its accessory system

Assignee: Arbel Medical Ltd.
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Quick Facts
Patent No.
US 7,731,711
App. No.
12/336,866
Granted
Jun 8, 2010
Kind
B2
Abstract

The invention proposes a cryosurgical instrument and its accessory system operating on the base of a refrigerant evaporation. The invention comprises combination of some technical solutions. Flow in a central lumen of the cryosurgical instrument has oscillating character; the refrigerant is provided on the internal surface of the distal cryotip in the form of separated portions. 2. The internal surface of the distal cryotip of the cryosurgical instrument is covered by a porous coating, which soaks completely one portion of the refrigerant. 3. Vapors obtained as a result of the refrigerant boiling on the porous coating of the cryotip are removed through the central lumen into the atmosphere. Combination of these technical solutions allows to construct a safely cryosurgical instrument with high freezing power and small outer diameter. The proposed cryosurgical instrument may be designed as a flexible cryocatheter or as a rigid cryoprobe.

Claims (16)

1. A method for cryogenic treatment of a patient, comprising:

contacting a portion of the patient with a cryosurgical instrument, said instrument having a tip;

delivering a cryogen to said tip; and

repeating said delivering said cryogen to said tip at least once while said tip is in contact with at least a portion of the patient, wherein controlling said delivering of said cryogen to said tip also controls temperature at said tip, such that the delivering and the repeating said delivering produce at least one freezing stage and at least one higher temperature freezing stage, and wherein said instrument comprises a plurality of valves for controlling said delivering said cryogen and wherein said repeating said delivering said cryogen to said tip at least once comprises: closing a valve to stop delivering said cryogen, and opening a valve to again deliver said cryogen, by opening a first valve of said plurality of valves to expel said cryogen to the atmosphere, closing said first valve, and opening a second valve of said plurality of valves to deliver said cryogen.

2. The method of claim 1 , wherein said portion of the patient comprises a blood vessel.

3. The method of claim 2 , wherein the cryogenic treatment is for prevention of restenosis.

4. The method of claim 1 , wherein said instrument further comprises a control unit and wherein said control unit controls said opening and said closing of said valves to control temperature at said tip.

5. The method of claim 4 , further comprising determining said temperature at said tip by said control unit; and controlling said opening and said closing of said valves by said control unit according to said temperature.

6. The method of claim 1 , wherein said delivering said cryogen to said tip comprises:

pressurizing said cryogen for rapid delivery to said tip.

7. The method of claim 6 , wherein said pressurizing comprises applying gas to said cryogen.

8. The method of claim 1 , wherein said cryogen comprises a plurality of cryogens having different properties.

9. The method of claim 1 , wherein said cryogen comprises at least one cryogenic liquid.

10. The method of claim 9 , wherein said cryogen comprises a plurality of cryogenic liquids.

11. The method of claim 1 , further comprising ablating tissue of said portion of the patient through said at least one freezing stage and said at least one higher temperature freezing stage.

12. The method of claim 1 , wherein said cryogen is delivered in a plurality of portions and wherein said temperature is controlled at said tip according to a frequency of repeating said delivering of said portions of said cryogen to said tip.

Assignments (10)
CORRECTIVE ASSIGNMENT TO CORRECT THE REMOVE APPLICATION 11759915 AND REPLACE IT WITH APPLICATION 11759935 PREVIOUSLY RECORDED ON REEL 040925 FRAME 0001. ASSIGNOR(S) HEREBY CONFIRMS THE RELEASE OF SECURITY INTEREST. Recorded Feb 17, 2020
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: NXP, B.V. F/K/A FREESCALE SEMICONDUCTOR, INC.
Reel/Frame 052917/0001 →
CORRECTIVE ASSIGNMENT TO CORRECT THE REMOVE APPLICATION 11759915 AND REPLACE IT WITH APPLICATION 11759935 PREVIOUSLY RECORDED ON REEL 040928 FRAME 0001. ASSIGNOR(S) HEREBY CONFIRMS THE RELEASE OF SECURITY INTEREST. Recorded Jan 17, 2020
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: NXP B.V.
Reel/Frame 052915/0001 →
CORRECTIVE ASSIGNMENT TO CORRECT THE REMOVE APPLICATION 11759915 AND REPLACE IT WITH APPLICATION 11759935 PREVIOUSLY RECORDED ON REEL 037486 FRAME 0517. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT AND ASSUMPTION OF SECURITY INTEREST IN PATENTS. Recorded Dec 10, 2019
From: CITIBANK, N.A.
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 053547/0421 →
RELEASE OF SECURITY INTEREST Recorded Nov 7, 2016
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: NXP B.V.
Reel/Frame 040928/0001 →
RELEASE OF SECURITY INTEREST Recorded Sep 21, 2016
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: NXP, B.V., F/K/A FREESCALE SEMICONDUCTOR, INC.
Reel/Frame 040925/0001 →
ASSIGNMENT AND ASSUMPTION OF SECURITY INTEREST IN PATENTS Recorded Jan 12, 2016
From: CITIBANK, N.A.
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 037486/0517 →
RELEASE OF SECURITY INTEREST Recorded Sep 18, 2013
From: ISLAND VENTURES LTD.
To: ICECURE MEDICAL LTD.
Reel/Frame 031232/0576 →
CHANGE OF NAME Recorded Jun 24, 2013
From: ARBEL MEDICAL LTD.
To: ICECURE MEDICAL LTD.
Reel/Frame 030675/0960 →
SECURITY AGREEMENT Recorded Jun 19, 2013
From: ICECURE MEDICAL LTD.
To: ISLAND VENTURES LTD.
Reel/Frame 030659/0040 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2008
From: LEVIN, ALEXANDER
To: ARBEL MEDICAL, LTD.
Reel/Frame 021993/0506 →
Priority Claims (1)
IL 151486 · Aug 26, 2002 · national
Continuity (3)
Continuation 1153105800 · Sep 12, 2006
Continuation 1063790400 · Aug 11, 2003
Related Publication 20090125008A1 · May 14, 2009