Porous polymer coating for tooth whitening
View Patent ↗The present invention relates to a tooth-whitening composition comprising (i) a substantially water-insoluble and substantially non-degradable polymer matrix component capable of adhering to the surface of a tooth, provided that if the polymer matrix component is in non-solid form, it is solidifiable by chemical alteration; and (ii) gas- or liquid-filled pores embedded in said polymer matrix component, wherein at least a portion of said gas- or liquid-filled pores have at least one size dimension in the range of about 70 nm to about 5 microns, and wherein the gas- or liquid-filled pores and polymer matrix component possess a difference in refractive index of at least 0.1. The invention is also directed to a tooth-whitening system containing the above composition in combination with an applicator device. The invention is also directed to methods for applying the tooth-whitening composition onto teeth.
1. A tooth-whitening solid film composition comprising:
(i) a water-insoluble and substantially non-degradable matrix component capable of adhering to the surface of a tooth, wherein said matrix component is a solid polymer matrix comprising a vinyl-addition polymer, wherein at least a portion of said vinyl-addition polymer is derived from at least two monomer types, each containing an acrylate group, the first monomer type according to the formula:
wherein R 1 , R 2 , and R 3 independently represent a hydrogen atom, nitrile group, fluorine atom, chlorine atom, or a saturated or unsaturated hydrocarbon group containing 1-6 carbon atoms, and R 4 represents a hydrogen atom or a saturated or unsaturated hydrocarbon group containing 1-6 carbon atoms, wherein said hydrocarbon group can be substituted by one or more nitrile groups, fluorine atoms, or chlorine atoms;
and the second monomer type according to the formula:
wherein R 5 , R 6 , and R 7 are independently selected from a hydrogen atom, nitrile group, fluorine atom, chlorine atom, and a saturated or unsaturated hydrocarbon group containing 1-6 carbon atoms optionally substituted by one or more groups selected from nitrile groups, fluorine atoms, chlorine atoms, and hydroxyl groups; and R 8 is a hydrogen atom or a saturated or unsaturated hydrocarbon group containing 1-6 carbon atoms optionally substituted by one or more groups selected from nitrile groups, fluorine atoms, chlorine atoms, and hydroxyl groups; wherein at least one of R 5 , R 6 , R 7 , and R 8 is a saturated or unsaturated hydrocarbon group substituted by at least one hydroxyl group, provided that the composition according to Formula (1) is present in an amount from 40 wt % to 95 wt % with respect to the total weight of Formulas (1) and (3); and
(ii) air-filled pores embedded in said matrix component, wherein the pore sizes range from about 100 nm to about 2 microns, the pores account for about 5% to about 60% by volume of the solid film composition, and the film is no more than 350 microns thick and has increased whiteness.
2. The composition of claim 1 , wherein the pore and polymer matrix components possess a difference in refractive index of at least 0.1.
3. The composition of claim 1 , wherein the film is no more than 300 microns thick.
4. The composition of claim 1 , wherein said solid film has a thickness in the range of about 20-100 microns.
5. The composition of claim 1 , wherein the composition is capable of increasing the CIE lightness index of a tooth by at least 10 units.
6. The composition of claim 1 , wherein the composition is capable of increasing the CIE lightness index of a tooth by at least 20 units.
7. The composition of claim 1 , wherein at least 80% of the pore sizes range from about 100 nm to about 1 micron.
8. The composition of claim 1 , wherein at least 80% of the pore sizes range from about 200 nm to about 1 micron.
9. A method for whitening teeth, the method comprising applying the tooth-whitening composition of claim 1 .
10. The composition of claim 1 , wherein the composition according to Formula (1) is present in an amount from 75 wt % to 95 wt % with respect to the total weight of Formulas (1) and (3).