IP Library Granted Patent US 8,137,958
Granted Patent B2
US 8,137,958 · App. 12/340,132 · Granted Mar 20, 2012

Active grip filter plug for sample collection devices

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Quick Facts
Patent No.
US 8,137,958
App. No.
12/340,132
Granted
Mar 20, 2012
Kind
B2
Abstract

A system for collecting a biological sample includes a collection device comprising a cylindrical body having a bore extending there through and a filter membrane disposed at one end thereof; a filter plug having an insert configured for insertion into the bore; a collar concentrically mounted about the exterior surface of the insert and configured for insertion into the bore; and a gasket disposed about the exterior surface of the insert, wherein an outer dimension of the gasket is variable in response to relative movement between the collar and the insert, and wherein the gasket has a cross section with two end portions and a mid portion that is located radially further away from the insert than the two end portions.

Claims (13)

1. A system for collecting a biological sample, comprising:

a collection device comprising a cylindrical wall defining a bore extending therethrough and a filter membrane disposed at one end thereof;

a filter plug having a cylindrical insert sized and configured for insertion into the bore of the collection device, the filter plug having a flanged proximal end extending radially outward from an exterior surface of the filter plug insert;

a cylindrical collar concentrically mounted about, and movable relative to, the exterior surface of the filter plug insert, the collar sized and configured for insertion into an annular space defined by the exterior surface of the filter plug insert and an interior surface of the collection device; and

a compressible annular gasket disposed about the exterior surface of the filter plug insert between a proximal end of the collar and the flanged proximal end of the filter plug insert, such that movement of the collar towards the flanged proximal end of the filter plug insert compresses and expands the gasket radially outward from the exterior surface of the filter plug insert, so as to form a seal between and thereby engage the the filter plug insert to the collection device.

2. The system of claim 1 , the gasket having an outer surface with a bell-shaped cross-sectional profile when in a non-compressed state.

3. The system of claim 1 , wherein the filter plug insert and collar are moveable with respect to one another to form a variable width groove between the flanged proximal end of the insert and the proximal end of the collar, the gasket being disposed in the groove.

4. The system of claim 1 , wherein the proximal end of the collar comprises a blunt end.

5. The system of claim 1 , wherein the collar comprises a flanged end at a proximal end thereof, the flanged end dimensioned to limit movement of the collar within the bore of the collection device.

6. The system of claim 1 , wherein the insert has a groove for accommodating the gasket.

7. The system of claim 6 , wherein the gasket has a surface facing the insert, and a recess formed at the surface.

8. The system of claim 1 , wherein the gasket is made from a liquid silicone rubber.

9. The system of claim 1 , wherein the gasket is made from a material having a hardness of at least 30 durometer.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 4, 2009
From: GRIMES, ERIC E.; SCAMPINI, STEVEN A.; OLIVA, RYAN; HA, TUAN
To: CYTYC CORPORATION
Reel/Frame 022346/0796 →