Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
The present invention provides compounds that have excellent antifungal action, and are also excellent in terms of properties, such as solubility in water and safety. The compounds are represented by formula (I): The present invention is also directed to a pharmaceutical composition comprising the compound, an antifungal agent comprising the compound as an active ingredient, and a method for preventing or treating a fungal disease by administering the compound.
1. A compound of 2-amino-1-((phosphonooxy)methyl)-3-(3-((4-((2-pyridinyloxy)methyl)phenyl)methyl)-5-isoxazolyl) -pyridinium represented by:
or a salt thereof
2. A pharmaceutical composition comprising the compound or the salt thereof according to claim 1 .
3. A method for treating a fungal disease by administering a pharmaceutically effective amount of the compound or the salt thereof according to claim 1 .