Markers for use in brachytherapy and other radiation therapy that resist migration and rotation
View Patent ↗In an embodiment, an implantable marker, which is adapted to be implanted into patient tissue using a hollow needle, includes a marker body including a radiopaque material and a polymeric material that encapsulates at least a portion of the marker body. In an embodiment, an outer surface of the encapsulating material includes one or more protrusions to reduce a tendency of the marker to migrate and rotate within a patient's body after implantation.
1. An implantable marker, comprising:
a longitudinal marker body including a radiopaque material; and
a polymeric material that encapsulates at least a portion of the marker body;
wherein an outer surface of the polymeric material includes two or more rows of protrusions to reduce a tendency of the marker to migrate and rotate within a patient's body after implantation;
wherein each of said rows of protrusions includes a plurality of rectangular knobs having sidewalls substantially perpendicular to the longitudinal marker body; and
wherein the implantable marker is adapted to be implanted into patient tissue using a hollow needle.
2. The implantable marker of claim 1 , wherein the polymeric material is bio-absorbable.
3. The implantable marker of claim 1 , wherein the polymeric material is molded to encapsulate at least a portion of the marker body.
4. The implantable marker of claim 1 , wherein the polymeric material is molded to completely encapsulate the marker body.
5. The implantable marker of claim 1 , wherein the radiopaque material comprises gold or tungsten.
6. The implantable marker of claim 1 , wherein the implantable marker is adapted to be at least temporarily stored within a cartridge adapted for use with a brachytherapy applicator having a hollow needle, where the cartridge is adapted to load the implantable marker into the hollow needle.
7. An implantable marker, comprising:
a longitudinal marker body that is at least partially radiopaque; and
a polymeric material molded to completely encapsulate the marker body;
wherein an outer surface of the polymeric material includes two or more rows of protrusions to reduce a tendency of the marker to migrate and rotate within a patient's body after implantation;
wherein each of said rows of protrusions includes a plurality of rectangular knobs having sidewalls substantially perpendicular to the longitudinal marker body; and
wherein the implantable marker is adapted to be implanted into patient tissue using a hollow needle.
8. The implantable marker of claim 7 , wherein:
the protrusions are made from the polymeric material that encapsulates the marker body; and
the polymeric material is bio-absorbable.
9. The implantable marker of claim 7 , wherein the protrusions are made of a non bio-absorbable material that is attached to the polymeric material.
10. The implantable marker of claim 7 , wherein the protrusions are defined by a shape of a mold that is used to encapsulate the marker.
11. The implantable marker of claim 7 , wherein each protrusion extends at least 0.002 inches beyond portions of the material where there is not a protrusion.
12. The implantable marker of claim 7 , wherein the implantable marker is adapted to be at least temporarily stored within a cartridge adapted for use with a brachytherapy applicator having a hollow needle, where the cartridge is adapted to load the implantable marker into the hollow needle.
13. An implantable marker, comprising:
a member with a longitudinal body, which longitudinal body has a first end and a second end, said member is at least partially radiopaque; and
a polymeric material molded to completely encapsulate the member;
wherein the implantable marker is adapted to be implanted into patient tissue using a hollow needle; and
wherein a portion of the molded polymeric material extends in a longitudinal direction from at least one of the first end and the second end of the longitudinal body of the member to reduce a tendency of the member to migrate and rotate within a patient's body after implantation of the member.
14. The implantable marker of claim 13 , wherein:
the member has a first length; and
the polymeric material molded to completely encapsulate the member causes the member to have a second length that is greater than the first length.
15. The implantable marker of claim 13 , wherein the portion of the molded polymeric material, that extends in the longitudinal direction with respect to the member, includes a void or groove that is adapted to have at least some patient tissue will occupy after implantation of the marker.
16. The implantable marker of claim 13 , wherein implantable marker is adapted to be at least temporarily stored within a cartridge adapted for use with a brachytherapy applicator having a hollow needle, where the cartridge is adapted to load the implantable marker into the hollow needle.
17. The implantable marker of claim 13 wherein said portion is an anchor.
18. The implantable marker of claim 13 wherein said portion is a tab.
19. An implantable marker, comprising:
a longitudinal marker body including a radiopaque material; and
a polymeric material that encapsulates at least a portion of the marker body;
wherein an outer surface of the polymeric material includes two or more rows of protrusions to reduce a tendency of the marker to migrate and rotate within a patient's body after implantation;
wherein each of said rows of protrusions includes a plurality of rectangular knobs having sidewalls substantially perpendicular to the longitudinal marker body;
wherein each of said rows of protrusions is provided longitudinally along the longitudinal marker body; and
wherein the implantable marker is adapted to be implanted into patient tissue using a hollow needle.
20. An implantable marker, comprising:
a longitudinal marker body that is at least partially radiopaque; and
a polymeric material molded to completely encapsulate the marker body;
wherein an outer surface of the polymeric material includes two or more rows of protrusions to reduce a tendency of the marker to migrate and rotate within a patient's body after implantation;
wherein each of said rows of protrusions includes a plurality of rectangular knobs having sidewalls substantially perpendicular to the longitudinal marker body;
wherein each of said rows of protrusions is provided longitudinally along the longitudinal marker body; and
wherein the implantable marker is adapted to be implanted into patient tissue using a hollow needle.