Methods and devices for quantitative analysis of x-ray images
View Patent ↗The present invention relates to network enabled analysis of x-ray images. Also described are devices comprising calibration phantoms; methods of using these devices; methods of formulating databases containing information regarding x-ray images; the databases themselves; and methods of manipulating the information and databases.
1. An x-ray assembly for determining bone mineral density comprising:
an x-ray film holder;
x-ray film; and
a calibration phantom comprising at least one marker positioned in an area of known density.
2. The assembly according to claim 1 , wherein the calibration phantom projects free of bone tissue.
3. The assembly of claim 1 , wherein the calibration phantom is attached to the x-ray film holder or a detector system.
4. The assembly of claim 1 , wherein the calibration phantom is integral to the x-ray film holder.
5. The assembly of claim 1 , wherein the x-ray assembly is a dental x-ray assembly.
6. The assembly of claim 1 , wherein the calibration phantom comprises a stepwedge.
7. The assembly of claim 1 , wherein the calibration phantom comprises a plurality of fluid-filled chambers.
8. The assembly of claim 1 , wherein the marker is a geometric pattern selected from the group consisting of circles, stars, squares, crescents, ovals, multiple-sided objects, irregularly shaped objects and combinations thereof.
9. An x-ray assembly for determining bone mineral density comprising:
an x-ray film holder;
x-ray film; and
a calibration phantom comprising at least one marker positioned in an area of known density, wherein the calibration phantom is attached to the x-ray film.
10. The assembly of claim 9 , wherein the calibration phantom is integral to the x-ray film.
11. The assembly of claim 9 , wherein the calibration phantom is included between two of the physical layers of the x-ray film.
12. The assembly of claim 9 , wherein the calibration phantom is included within one of the physical layers of the x-ray film.
13. A method of accurately determining bone mineral density of an x-ray image, the method comprising:
providing an assembly according to claim 1 , wherein the calibration phantom is positioned such that x-rays pass through a subject and the calibration phantom simultaneously, wherein the calibration phantom projects free of materials that alter its' apparent density;
creating an image of the phantom and the portion of the subject's anatomy; and
comparing the image of the phantom and the subject's anatomy to determine bone mineral density of the subject.
14. The method of claim 13 , wherein the x-ray image is a dental x-ray.
15. The method of claim 13 , wherein said comparing is performed in a network environment.
16. A kit comprising a calibration phantom with an integrated reference marker; an x-ray imaging assembly and computer readable media encoded with computer software programs that when installed and executed on a computer analyze and assess an x-ray image and provide a computer readout showing bone mineral density.