Compositions Comprising Nebivolol
Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.
1 - 36 . (canceled)
37 . A composition comprising nebivolol or a pharmaceutically acceptable salt thereof, and valsartan or a pharmaceutically acceptable salt thereof.
38 . The composition of claim 37 , wherein the nebivolol or pharmaceutically acceptable salt thereof, and valsartan or pharmaceutically acceptable salt thereof, form a single oral dosage form.
39 . A method of treating or preventing hypertension in a patient in need thereof, comprising administering to said patient an effective amount of nebivolol or a pharmaceutically acceptable salt thereof, and valsartan or a pharmaceutically acceptable salt thereof.
40 . The method of claim 39 , wherein the nebivolol or pharmaceutically acceptable salt thereof, and valsartan or pharmaceutically acceptable salt thereof, are orally administered.
41 . The method of claim 39 , wherein the nebivolol or pharmaceutically acceptable salt thereof, and valsartan or pharmaceutically acceptable salt thereof, are orally administered in a single dosage form.
42 . The method of claim 39 , wherein the nebivolol or pharmaceutically acceptable salt thereof, and valsartan or pharmaceutically acceptable salt thereof, are orally administered in separate dosage forms.
43 . A method of treating or preventing cardiovascular disease in a patient in need thereof, comprising administering to said patient an effective amount of nebivolol or a pharmaceutically acceptable salt thereof, and valsartan or a pharmaceutically acceptable salt thereof.
44 . The method of claim 43 , wherein the nebivolol or pharmaceutically acceptable salt thereof, and valsartan or pharmaceutically acceptable salt thereof, are orally administered.
45 . The method of claim 43 , wherein the nebivolol or pharmaceutically acceptable salt thereof, and valsartan or pharmaceutically acceptable salt thereof, are orally administered in a single dosage form.
46 . The method of claim 43 , wherein the wherein the nebivolol or pharmaceutically acceptable salt thereof, and valsartan or pharmaceutically acceptable salt thereof, are orally administered in separate dosage forms.