IP Library › Patent Application 12368807
Patent Application
App. No. 12/368,807

FORMULATION FOR CONTROLLED RELEASE OF DRUGS BY COMBINING HYDROPHILIC AND HYDROPHOBIC AGENTS

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
12/368,807
Abstract

Combinations of hydrophilic and hydrophobic entities in a biodegradable sustained release implant are shown to modulate each other's rate of release. Formulations of a therapeutically active agent and modulator provide substantially constant rate of release for an extended period of time.

Claims (7)

1 . A monolithic implant for treating an ocular condition, the implant comprising:

(a) a biodegradable polymeric matrix;

(b) an anti-inflammatory steroid homogenously distributed through the polymeric matrix, and;

(c) a saccharide for modifying release of the steroid from the polymeric matrix.

2 . The implant of claim 1 , wherein the saccharide is a monosaccharide, a disaccharide or a polysaccharide.

3 . The implant of claim 1 wherein the polymeric matrix comprises a copolymer of glycolic and lactic acid.

4 . A method for treating an ocular condition, the method comprising the step of administering to the vitreous cavity of an eye, a monolithic implant comprising a biodegradable polymeric matrix, an anti-inflammatory steroid homogenously distributed through the polymeric matrix, and a saccharide for modifying release of the steroid from the polymeric matrix.