IP Library › Granted Patent US 7,947,265
Granted Patent B2
US 7,947,265 · App. 12/375,730 · Granted May 24, 2011

Fusion proteins and methods for modulation of immune response

Assignee: McGill University
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,947,265
App. No.
12/375,730
Granted
May 24, 2011
Kind
B2
Abstract

A fusion protein comprising GM-CSF and IL-15 is described. The fusion protein has unexpected immune suppressive properties and is useful in a variety of therapeutic applications.

Claims (3)

1. A method of inhibiting graft rejection of a transplanted cell comprising administering an effective amount of a GM-CSF and IL-15 conjugate protein comprising the sequence shown in SEQ ID NO:2 or 4 to an animal in need thereof.

2. The method according to claim 1 wherein said cell is a xenogeneic cell.

3. The method according to claim 1 wherein said cell is an allogeneic cell.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 27, 2009
From: GALIPEAU, JACQUES; RAFEI, MOUTIH
To: MCGILL UNIVERSITY
Reel/Frame 022459/0606 →
Continuity (2)
Provisional Application 60821194 · Aug 2, 2006
Related Publication 20100021421A1 · Jan 28, 2010