Granted Patent
B2
US 8,101,630 · App. 12/383,906 · Granted Jan 24, 2012
Extended release opioid abuse deterrent compositions and methods of making same
View Patent ↗
Loading inventors, assignments & file history…
Abstract
This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.
Claims (8)
1. An extended release abuse deterrent dosage form comprising:
a. a core matrix comprising a blended mixture of:
(a) PEO having a molecular weight of from about 300,000 to about 5,000,000;
(b) magnesium stearate; and
(c) oxycodone or a pharmaceutically acceptable salt thereof;
wherein the matrix is heated to melt at least a portion of the PEO included in the matrix; and
b. PEG applied onto the core matrix;
wherein the dosage form provides extended release of the drug.
Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE PROPERTY #14338143 PREVIOUSLY RECORDED ON REEL 033561 FRAME 0296. ASSIGNOR(S) HEREBY CONFIRMS THE LICENSE.
Recorded Feb 25, 2016
From: ACURA PHARMACEUTICALS, INC
To: HIGHLAND PHARMACEUTICALS, LLC AND ITS AFFILIATES
Reel/Frame 038315/0279 →
LICENSE
Recorded Aug 19, 2014
From: ACURA PHARMACEUTICALS, INC.; HIGHLAND PHARMACEUTICALS, LLC
To: HIGHLAND PHARMACEUTICALS, LLC
Reel/Frame 033561/0296 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 2, 2011
From: KUMAR, VIJAI; DIXON, DAVID; TEWARI, DIVYA; WADGAONKAR, DILIP B
To: HALSEY DRUG COMPANY, INC.
Reel/Frame 026380/0183 →
CHANGE OF NAME
Recorded Jun 2, 2011
From: HALSEY DRUG CO., INC.
To: ACURA PHARMACEUTICALS, INC.
Reel/Frame 026382/0156 →