IP Library Granted Patent US 8,101,630
Granted Patent B2
US 8,101,630 · App. 12/383,906 · Granted Jan 24, 2012

Extended release opioid abuse deterrent compositions and methods of making same

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Quick Facts
Patent No.
US 8,101,630
App. No.
12/383,906
Granted
Jan 24, 2012
Kind
B2
Abstract

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.

Claims (8)

1. An extended release abuse deterrent dosage form comprising:

a. a core matrix comprising a blended mixture of:

(a) PEO having a molecular weight of from about 300,000 to about 5,000,000;

(b) magnesium stearate; and

(c) oxycodone or a pharmaceutically acceptable salt thereof;

wherein the matrix is heated to melt at least a portion of the PEO included in the matrix; and

b. PEG applied onto the core matrix;

wherein the dosage form provides extended release of the drug.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE PROPERTY #14338143 PREVIOUSLY RECORDED ON REEL 033561 FRAME 0296. ASSIGNOR(S) HEREBY CONFIRMS THE LICENSE. Recorded Feb 25, 2016
From: ACURA PHARMACEUTICALS, INC
To: HIGHLAND PHARMACEUTICALS, LLC AND ITS AFFILIATES
Reel/Frame 038315/0279 →
LICENSE Recorded Aug 19, 2014
From: ACURA PHARMACEUTICALS, INC.; HIGHLAND PHARMACEUTICALS, LLC
To: HIGHLAND PHARMACEUTICALS, LLC
Reel/Frame 033561/0296 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 2, 2011
From: KUMAR, VIJAI; DIXON, DAVID; TEWARI, DIVYA; WADGAONKAR, DILIP B
To: HALSEY DRUG COMPANY, INC.
Reel/Frame 026380/0183 →
CHANGE OF NAME Recorded Jun 2, 2011
From: HALSEY DRUG CO., INC.
To: ACURA PHARMACEUTICALS, INC.
Reel/Frame 026382/0156 →