IP Library Granted Patent US 8,733,556
Granted Patent B2
US 8,733,556 · App. 12/387,576 · Granted May 27, 2014

Method for reducing performance variability of multi-layer filters

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Quick Facts
Patent No.
US 8,733,556
App. No.
12/387,576
Granted
May 27, 2014
Kind
B2
Abstract

Multi-layer membrane devices with reduced performance variability, and method of reducing performance variability of such devices. The variability is reduced by combining two or more membranes with similar pore sizes, and carefully selecting the upstream membrane based upon its performance rating, in order to control the performance of the overall device. Selective layering reduces the capacity range of the device when compared to random layering, with the mean capacity greater than overall population mean. The flux range also can be reduced, with the mean near the overall population mean. The LRV range also can be reduced, with the mean LRV near or higher than the overall population mean.

Claims (20)

1. A method of reducing filter-to-filter performance variability in a multi-layered filtration device including an upstream filter membrane and a downstream filter membrane, wherein each said membrane has substantially the same pore size rating, comprising:

a. selecting a target performance characteristic value selected from the group consisting of capacity, permeability and retention for said device;

b. determining the values of the same performance characteristic as said target performance characteristic of a plurality of different membrane batches;

c. selecting as said upstream membrane a membrane from said plurality of different membrane batches having a first performance characteristic value or range of values;

d. selecting as said downstream membrane a membrane from said plurality of different membrane batches having a second performance characteristic value or range of values; wherein said first performance characteristic value or range of values is higher than said second performance characteristic value or range of values and is selected such that said target performance characteristic value is achieved.

2. The method of claim 1 , wherein said performance characteristic is capacity.

3. The method of claim 1 , wherein said performance characteristic is retention.

4. The method of claim 1 , wherein said performance characteristic is permeability.

5. The method of claim 1 , wherein said first performance characteristic is the highest performance characteristic of all membranes within said plurality of membrane batches.

6. The method of claim 5 , wherein said second performance characteristic is the lowest performance characteristic of all membrane within said plurality of membrane batches.

7. The method of claim 1 , wherein said first performance characteristic is the second highest performance characteristic of all membranes within said plurality of membrane batches.

8. The method of claim 7 , wherein said second performance characteristic is the second lowest performance characteristic of all membrane within said plurality of membrane batches.

9. A method of reducing filter-to-filter performance variability in a multi-layered filtration device including an upstream filter membrane and a downstream filter membrane, wherein each said membrane has substantially the same pore size rating, comprising:

a. selecting a target performance characteristic value selected from the group consisting of capacity, permeability and retention for said device;

b. determining the values of the same performance characteristic as said target performance characteristic of a plurality of different membrane batches;

c. selecting as said upstream membrane a membrane from said plurality of different membrane batches having a first performance characteristic value or range of values;

d. selecting as said downstream membrane a membrane from said plurality of different membrane batches having a second performance characteristic value or range of values; wherein said first performance characteristic value or range of values is lower than said second performance characteristic value or range of values and is selected such that said target performance characteristic value is achieved.

10. The method of claim 9 , wherein said performance characteristic is capacity.

11. The method of claim 9 , wherein said performance characteristic is retention.

12. The method of claim 9 , wherein said performance characteristic is permeability.

Assignments (3)
CHANGE OF ADDRESS Recorded Feb 15, 2018
From: EMD MILLIPORE CORPORATION
To: EMD MILLIPORE CORPORATION
Reel/Frame 045341/0166 →
CHANGE OF NAME Recorded Jan 31, 2012
From: MILLIPORE CORPORATION
To: EMD MILLIPORE CORPORATION
Reel/Frame 027620/0891 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2009
From: GIGLIA, SAL; KRISHNAN, MANI; SATAV, NITIN
To: MILLIPORE CORPORATION
Reel/Frame 022986/0818 →