Kinase inhibitor
View Patent ↗The invention is directed to a compound of formula (I): and the prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their prodrugs. Such a compound has valuable pharmaceutical properties, in particular the ability to inhibit protein kinases.
1. A compound of formula (I):
or a corresponding N-oxide, or a prodrug; or a pharmaceutically acceptable salt of such of compound; or an N-oxide or a prodrug of the salt.
2. A pharmaceutical composition, comprising a compound according to claim 1 , together with at least one pharmaceutically acceptable carrier or excipient.
3. The compound according to claim 1 , wherein the salt is selected from:
hydrochloride, hydrobromide, sulphate, phosphate, nitrate, sulfamate, acetate, citrate, lactate, tartrate, malonate, oxalate, salicylate, propionate, succinate, fumarate, maleate, methylene-bis-b-hydroxynaphthoate, gentisate, isethionate, di-p-toluoyltartrate, methane-sulfonate, ethanesulfonate, benzenesulfonate, p-toluenesulfonate, cyclohexylsulfamate and quinate.
4. The compound according to claim 1 , wherein the salt is hydrochloride.
5. The compound according to claim 1 , wherein the salt is acetate.
6. The compound according to claim 1 , wherein the salt is citrate.