IP Library › Patent Application 12403081
Patent Application
App. No. 12/403,081

PHARMACEUTICAL SUSPENSION COMPOSITION

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Quick Facts
Patent No.
US None
App. No.
12/403,081
Abstract

An aqueous oral liquid pharmaceutical composition system with reduced propensity for agglomeration and phase separation which is particularly amendable to the suspension of one or more pharmaceutical actives that are substantially insoluble in water. The oral liquid pharmaceutical composition may further comprise pharmaceutical actives that are soluble in water and dissolve in the aqueous medium. In the composition of the invention both suspended and any dissolved active agents are distributed homogeneously.

Claims (10)

1 .- 24 . (canceled)

25 . A method of preparing an oral liquid pharmaceutical composition comprising:

a. preparing a suspending system, including suspended components in an aqueous medium;

b. suspending at least one substantially insoluble first pharmaceutical active in the suspending system; and

c. matching the true density of the at least one substantially insoluble first pharmaceutical active and the suspended components of the suspending system with the specific gravity of the aqueous medium.

26 . The method of claim 25 further comprising de-aerating the composition by subjecting it to vacuum.

27 . The method of claim 25 further comprising dissolving in the aqueous medium at least one second pharmaceutical active soluble in the aqueous medium.

28 . The method of claim 26 further comprising adding a surface modifying agent to the pharmaceutical composition.

29 . A method for treatment of pain and discomfort associated with at least one of headache, body ache, cold symptoms, flu symptoms, and allergy symptoms in humans comprising the administration to a human of a safe and effective amount of the pharmaceutical composition of claim 25 .

30 . A method for treatment of pain and discomfort associated with at least one of headache, body ache, cold symptoms, flu symptoms, and allergy symptoms in humans comprising the administration to a human of a safe and effective amount of the pharmaceutical composition of claim 27 .