Optimized multi-epitope constructs and uses thereof

Assignees: Epimmune Inc.; GENimmune N.V.

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Quick Facts

Patent No.: US 7,888,472
App. No.: 12/408,472
Granted: Feb 15, 2011
Kind: B2

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Abstract

The invention relates to the field of biology. In particular, it relates to multi-epitope nucleic acid and peptide vaccines and methods of designing such vaccines to provide increased immunogenicity.

Claims (6)

1. An isolated polypeptide encoded by a polynucleotide selected from the group consisting of: SEQ ID NO:205 and SEQ ID NO:207.

2. An isolated polypeptide selected from the group consisting of SEQ ID NO:206 and SEQ ID NO:208.

3. A composition comprising the polypeptide of claim 1 .

4. A method of inducing an immune response against hepatitis B virus (HBV) in an individual in need thereof, comprising administering the polypeptide of claim 1 to said individual.

5. A composition comprising the polypeptide of claim 2 .

6. A method of inducing an immune response against hepatitis B virus (HBV) in an individual in need thereof, comprising administering the polypeptide of claim 2 to said individual.

Assignments (7)

CHANGE OF NAME Recorded Jul 16, 2010

From: PHARMEXA INC.

To: EPIMMUNE INC.

Reel/Frame 024699/0182 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 25, 2010

From: SETTE, ALESSANDRO; CHESNUT, ROBERT; NEWMAN, MARK J.; LIVINGSTON, BRIAN J.

To: EPIMMUNE INC.

Reel/Frame 024595/0179 →

MERGER Recorded Jun 25, 2010

From: EPIMMUNE INC.

To: IDM PHARMA, INC.