IP Library Granted Patent US 8,135,472
Granted Patent B2
US 8,135,472 · App. 12/415,200 · Granted Mar 13, 2012

Systems and methods for treating autism spectrum disorders (ASD) and related dysfunctions

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Quick Facts
Patent No.
US 8,135,472
App. No.
12/415,200
Granted
Mar 13, 2012
Kind
B2
Abstract

Systems and methods for treating autism spectrum disorders (ASD) and related dysfunctions are disclosed. A method in accordance with a particular embodiment includes determining that a patient suffers from an autistic disorder and, based at least in part on the determination, selecting a cortical signal delivery site. The method can further include implanting an electrode within the patient's skull and external to a cortical surface of the patient's brain, and treating the autistic disorder by applying electrical signals to the implanted electrode in conjunction administering an adjunctive therapy to the patient.

Claims (13)

1. A method for treating a patient dysfunction, comprising:

determining that the patient suffers from an autism spectrum disorder;

based at least in part on the determination that the patient suffers from an autism spectrum disorder, selecting a target neural population of the patient's brain, wherein the target neural population is selected from the group consisting of amygdala, superior temporal sulcus and Brodmann area 36 ;

applying electromagnetic signals to the target neural population; and

administering a training program to the patient to train the patient to recognize expressions of facial emotion thereby promoting cortical organization of the patient's brain by administering a behavioral adjunctive therapy in conjunction with delivering electromagnetic signals.

2. The method of claim 1 , further comprising identifying the target neural population as being hypoactive, and wherein delivering the electromagnetic signals includes increasing the activation level of the target neural population.

3. The method of claim 2 wherein delivering the electromagnetic signals includes delivering the electromagnetic signals at a frequency greater than about 5 Hz.

4. The method of claim 1 , further comprising identifying the target neural population as being hyperactive, and wherein delivering the electromagnetic signals includes decreasing the activation level of the target neural population.

5. The method of claim 4 wherein delivering the electromagnetic signals includes delivering the electromagnetic signals at a frequency of less than 5 Hz.

6. The method of claim 1 wherein delivering the electromagnetic signals includes delivering the electromagnetic signals from an implanted electrode positioned beneath the patient's skull and external to a cortical surface of the patient's brain.

7. The method of claim 1 wherein delivering the electromagnetic signals includes delivering the electromagnetic signals from a site external to the patient's skull.

8. The method of claim 7 wherein determining that the patient suffers from an autism spectrum disorder includes determining that a child patient suffers from an autism spectrum disorder, and wherein delivering the electromagnetic signals includes delivering the electromagnetic signals via transcranial magnetic stimulation.

9. The method of claim 1 wherein delivering the electromagnetic signals includes delivering the electromagnetic signals from an implanted electrode positioned beneath a cortical surface of the patient's brain.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2009
From: NORTHSTAR NEUROSCIENCE, INC.
To: ADVANCED NEUROMODULATION SYSTEMS, INC.
Reel/Frame 022813/0542 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 31, 2009
From: FOWLER, BRAD C.; MASSARO, DOMINIC W.
To: NORTHSTAR NEUROSCIENCE, INC.
Reel/Frame 022477/0814 →