CLAY-BASED HEMOSTATIC AGENTS AND DEVICES FOR THE DELIVERY THEREOF
A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.
1 . A hemostatic product comprising:
hemostatic device comprising:
a substrate; and
a hemostatic agent disposed on or into said substrate;
wherein the substrate is folded into a pleated form; and
a package containing the hemostatic device;
wherein the hemostatic product is prepared by a process comprising applying a vacuum.
2 . The product of claim 1 , wherein the substrate comprises gauze.
3 . The product of claim 1 , wherein the hemostatic agent comprises at least one of: a bioactive glass, a biological hemostat, a molecular sieve, diatomaceous earth, a clay material, and chitosan.
4 . The product of claim 3 , wherein the hemostatic agent comprises a clay material.
5 . The product of claim 4 , wherein the clay material comprises at least one of attapulgite, bentonite, and kaolin.
6 . The product of claim 5 , wherein the clay material comprises kaolin.
7 . The product of claim 1 , further comprising a release agent disposed on the substrate.
8 . A device comprising:
a substrate;
a hemostatic agent disposed on the substrate; and
a pharmaceutically active composition disposed on the substrate.
9 . The device of claim 8 , wherein the pharmaceutically active composition comprises an analgesic or an anti-inflammatory agent.
10 . The device of claim 9 , wherein the pharmaceutically active composition further comprises at least one of: an antibiotic, an antifungal agent, an anti-microbial agent, a silver ions, or copper ions.
11 . The device of claim 8 , wherein the pharmaceutically active agent comprises an analgesic.
12 . The device of claim 8 , wherein the pharmaceutically active agent comprises an anti-inflammatory agent.
13 . The device of claim 9 , wherein the hemostatic agent comprises a clay.
14 . The device of claim 13 , wherein the clay comprises kaolin.