METHOD OF TREATING OF DEMYELINATING DISEASES OR CONDITIONS
N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
1 . A method for improving walking ability of a patient afflicted with multiple sclerosis, comprising administering to the patient a therapeutically effective amount of a compound of formula
or a pharmaceutically acceptable salt thereof.
2 . The method according to claim 1 , wherein the pharmaceutically acceptable salt is hydrochloride salt.