IP Library › Granted Patent US 8,377,968
Granted Patent B2
US 8,377,968 · App. 12/420,793 · Granted Feb 19, 2013

N-piperidinyl acetamide derivatives as calcium channel blockers

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,377,968
App. No.
12/420,793
Granted
Feb 19, 2013
Kind
B2
Abstract

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing N-piperidinyl acetamide derivatives as shown in formula (1).

Claims (3)

1. A pharmaceutical composition comprising a compound having the structure:

or a pharmaceutically acceptable salt or conjugate thereof in admixture with a pharmaceutically acceptable excipient.

2. A method to treat epilepsy, said method comprising administering to a subject in need of such treatment an amount of the pharmaceutical composition of claim 1 effective to ameliorate epilepsy.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2018
From: TARO PHARMACEUTICALS INC.
To: MARK G. DEGIACOMO, CHAPTER 7 TRUSTEE OF EPIRUS BIOPHARMACEUTICALS, INC.
Reel/Frame 047435/0416 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2018
From: MARK G. DEGIACOMO, CHAPTER 7 TRUSTEE OF EPIRUS BIOPHARMACEUTICALS, INC.
To: PRAXIS PRECISION MEDICINES, INC.
Reel/Frame 047445/0370 →
MERGER Recorded Mar 24, 2016
From: ZALICUS PHARMACEUTICALS LTD.
To: TARO PHARMACEUTICALS INC.
Reel/Frame 038091/0087 →