Method for administering GLP-1 molecules
View Patent ↗The invention relates to formulations that demonstrate the feasibility of oral absorption comprising glucose-like peptide-1 compounds and specified delivery agents, and to methods of stimulating GLP-1 receptor in a subject in need of such stimulation, by administration of the formulation of the present invention.
1. A composition comprising (i) a GLP-1 compound of SEQ ID NO: 2 and (ii) a delivery agent having the formula
or a pharmaceutically acceptable salt thereof.
2. The composition of claim 1 , further comprising an excipient selected from pharmaceutically acceptable buffers, suspending agents, co-solvents, preservatives, isotonicity agents, and combinations thereof.
3. The composition of claim 1 , in the form of a tablet, capsule or particle.
4. The composition of claim 1 , wherein the GLP-1 compound is a GLP-1 derivative of SEQ ID NO: 2.