IP Library Granted Patent US 7,939,494
Granted Patent B2
US 7,939,494 · App. 12/421,590 · Granted May 10, 2011

Method for administering GLP-1 molecules

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Quick Facts
Patent No.
US 7,939,494
App. No.
12/421,590
Granted
May 10, 2011
Kind
B2
Abstract

The invention relates to formulations that demonstrate the feasibility of oral absorption comprising glucose-like peptide-1 compounds and specified delivery agents, and to methods of stimulating GLP-1 receptor in a subject in need of such stimulation, by administration of the formulation of the present invention.

Claims (5)

1. A composition comprising (i) a GLP-1 compound of SEQ ID NO: 2 and (ii) a delivery agent having the formula

or a pharmaceutically acceptable salt thereof.

2. The composition of claim 1 , further comprising an excipient selected from pharmaceutically acceptable buffers, suspending agents, co-solvents, preservatives, isotonicity agents, and combinations thereof.

3. The composition of claim 1 , in the form of a tablet, capsule or particle.

4. The composition of claim 1 , wherein the GLP-1 compound is a GLP-1 derivative of SEQ ID NO: 2.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 22, 2021
From: EMISPHERE TECHNOLOGIES, INC.
To: NOVO NORDISK NORTH AMERICA OPERATIONS A/S
Reel/Frame 056750/0169 →