METHODS OF TREATING NON-PAINFUL BLADDER DISORDERS USING ALPHA2DELTA SUBUNIT CALCIUM CHANNEL MODULATORS
A method is provided for treatment of non-painful bladder disorders, particularly non-painful overactive bladder without loss of urine. The method comprises administration of an α 2 δ subunit calcium channel modulator, including gabapentin, pregabalin, GABA analogs, fused bicyclic or tricyclic amino acid analogs of gabapentin, amino acid compounds, and other compounds that interact with the α 2 δ calcium channel subunit.
1 . A method for treating nocturia comprising administering a therapeutically effective amount of an α 2 δ subunit calcium channel modulator selected from the group consisting of Gabapentin and Pregabalin.
2 . A method for treating urinary frequency comprising administering a therapeutically effective amount of an α 2 δ subunit calcium channel modulator selected from the group consisting of Gabapentin and Pregabalin.
3 . A method for treating urinary urgency comprising administering a therapeutically effective amount of an α 2 δ subunit calcium channel modulator selected from the group consisting of Gabapentin and Pregabalin.